Brain tumor epidemiology: consensus from the Brain Tumor Epidemiology Consortium.

Published

Journal Article (Review)

Epidemiologists in the Brain Tumor Epidemiology Consortium (BTEC) have prioritized areas for further research. Although many risk factors have been examined over the past several decades, there are few consistent findings, possibly because of small sample sizes in individual studies and differences between studies in patients, tumor types, and methods of classification. Individual studies generally have lacked samples of sufficient size to examine interactions. A major priority based on available evidence and technologies includes expanding research in genetics and molecular epidemiology of brain tumors. BTEC has taken an active role in promoting understudied groups, such as pediatric brain tumors; the etiology of rare glioma subtypes, such as oligodendroglioma; and meningioma, which, although it is not uncommon, has only recently been registered systematically in the United States. There also is a pressing need for more researchers, especially junior investigators, to study brain tumor epidemiology. However, relatively poor funding for brain tumor research has made it difficult to encourage careers in this area. In this report, BTEC epidemiologists reviewed the group's consensus on the current state of scientific findings, and they present a consensus on research priorities to identify which important areas the science should move to address.

Full Text

Duke Authors

Cited Authors

  • Bondy, ML; Scheurer, ME; Malmer, B; Barnholtz-Sloan, JS; Davis, FG; Il'yasova, D; Kruchko, C; McCarthy, BJ; Rajaraman, P; Schwartzbaum, JA; Sadetzki, S; Schlehofer, B; Tihan, T; Wiemels, JL; Wrensch, M; Buffler, PA; Brain Tumor Epidemiology Consortium,

Published Date

  • October 2008

Published In

Volume / Issue

  • 113 / 7 Suppl

Start / End Page

  • 1953 - 1968

PubMed ID

  • 18798534

Pubmed Central ID

  • 18798534

Electronic International Standard Serial Number (EISSN)

  • 1097-0142

International Standard Serial Number (ISSN)

  • 0008-543X

Digital Object Identifier (DOI)

  • 10.1002/cncr.23741

Language

  • eng