Is RNA interference involved in intrinsic antiviral immunity in mammals?
Journal Article (Journal Article;Review)
RNA interference constitutes a key component of the innate immune response to viral infection in both plants and invertebrate animals and has been postulated to have a similar protective function in mammals. This perspective reviews the available data addressing whether RNA interference forms part of the mammalian innate immune response and concludes that the popular hypothesis in favor of that possibility remains far from proven and may not be valid.
Full Text
Duke Authors
Cited Authors
- Cullen, BR
Published Date
- June 2006
Published In
Volume / Issue
- 7 / 6
Start / End Page
- 563 - 567
PubMed ID
- 16715068
International Standard Serial Number (ISSN)
- 1529-2908
Digital Object Identifier (DOI)
- 10.1038/ni1352
Language
- eng
Conference Location
- United States