Recognition and cleavage of primary microRNA transcripts.
Published
Journal Article (Review)
MicroRNAs (miRNAs) are approx 22-nucleotide (nt)-long, single-stranded, endogenous, noncoding RNAs that are widely expressed in multicellular organisms. This chapter describes methods that allow the overexpression of human miRNAs and also discusses how primary miRNAs (pri-miRNAs), the much longer precursors of mature miRNAs, are processed in human cells, as well as in vitro.
Full Text
Duke Authors
Cited Authors
- Zeng, Y; Cullen, BR
Published Date
- 2006
Published In
Volume / Issue
- 342 /
Start / End Page
- 49 - 56
PubMed ID
- 16957366
Pubmed Central ID
- 16957366
International Standard Serial Number (ISSN)
- 1064-3745
Digital Object Identifier (DOI)
- 10.1385/1-59745-123-1:49
Language
- eng
Conference Location
- United States