Acquired immunodeficiency syndrome (AIDS).


Journal Article (Review)

The Acquired Immunodeficiency Syndrome (AIDS), caused by the human immunodeficiency virus (HIV), also called the human T-lymphotropic virus type III/lymphadenopathy-associated virus [HTLV-III/LAV], has affected over 23,000 people; more than half of those with the disease have died. The actual case fatality rate approaches 100%. AIDS affects all groups and classes of people, although some are at special risk. Distribution of the disease is worldwide. The illness' effects on the body are widespread; of special interest are the ophthalmologic manifestations. The eye may be infected by various viruses (cytomegalovirus, varicella-zoster virus, herpes simplex virus or HIV itself), toxoplasma gondii, candida sp, cryptococcus neoformans, M. tuberculosis, or M. avium-intracellulare. Kaposi's sarcoma may affect the eye as well. Retinal vascular abnormalities (e.g., cotton-wool spots, vasculitis) are not uncommon in AIDS. The syndrome may present with neuro-ophthalmologic manifestations. No effective treatment for the illness is currently available, although several hold promise and there is hope for an AIDS vaccine. Prevention of infection through reduction of risks appears to be the only defense against AIDS at this time.

Full Text

Duke Authors

Cited Authors

  • Schuman, JS; Orellana, J; Friedman, AH; Teich, SA

Published Date

  • May 1987

Published In

Volume / Issue

  • 31 / 6

Start / End Page

  • 384 - 410

PubMed ID

  • 3303395

Pubmed Central ID

  • 3303395

International Standard Serial Number (ISSN)

  • 0039-6257

Digital Object Identifier (DOI)

  • 10.1016/0039-6257(87)90031-2


  • eng

Conference Location

  • United States