Ultrastructure and clinicopathologic correlation of idiopathic preretinal macular fibrosis.

Journal Article (Journal Article)

Detailed light and electron microscopic examination of early idiopathic preretinal fibrosis lesions showed that the fibrosis consisted of a layer of glial cells on the retinal surface. Two cases supported the clinical observation that a glinting retinal reflex preceded the development of retinal folds and traction lines. In both cases there was a break in the inner limiting lamina through which glial cells migrated and, presumably, proliferated on the retinal surface. There was no evidence for vitreoretinal adhesions. The ultrastructural similarity of the lesion to preretinal glial membranes seen in other disease entities suggested the possibility of a common biochemical stimulus for glial cell migration and proliferation on the retinal surface.

Full Text

Duke Authors

Cited Authors

  • Bellhorn, MB; Friedman, AH; Wise, GN; Henkind, P

Published Date

  • March 1, 1975

Published In

Volume / Issue

  • 79 / 3

Start / End Page

  • 366 - 373

PubMed ID

  • 1121993

International Standard Serial Number (ISSN)

  • 0002-9394

Digital Object Identifier (DOI)

  • 10.1016/0002-9394(75)90608-x


  • eng

Conference Location

  • United States