Retinal pigment epithelial degeneration, partial retinal atrophy and macular hole in acute lymphocytic leukemia.

Journal Article (Journal Article)

A seven year old child with acute lymphocytic leukemia presented at autopsy with a macular hole, and degeneration of the retinal pigment epithelium and its overlying photoreceptors. She had been treated with cobalt 60, methotrexate, vincristine cyclophosphamide and prednisone. A review of the literature of similar findings as well as pigment epithelial degenerations from other causes is presented.

Full Text

Duke Authors

Cited Authors

  • Inkeles, DM; Friedman, AH

Published Date

  • 1975

Published In

Volume / Issue

  • 194 / 4 Suppl

Start / End Page

  • 253 - 261

PubMed ID

  • 1079418

International Standard Serial Number (ISSN)

  • 0065-6100

Digital Object Identifier (DOI)

  • 10.1007/BF00414672


  • eng

Conference Location

  • Germany