The isolated perfused frog eye: a useful preparation for the investigation of drug effects on retinal function.

Journal Article (Journal Article)

The isolated frog eye perfused through its ophthalmic artery with a modified oxygenated Sickel's media responds to light stimuli of different wavelengths in a manner similar to that observed in the frog eye in vivo for periods of 9 hr and longer. Short- and long-duration field potentials from the globe (ERG) and optic nerve (ONP) can be recorded simultaneously. Drugs perfused through the eye can be shown to modify components of the ERG and ONP and to alter the flow rate of the perfusion media through the eye.

Full Text

Duke Authors

Cited Authors

  • Friedman, AH; Marchese, AL

Published Date

  • May 1, 1981

Published In

Volume / Issue

  • 5 / 3

Start / End Page

  • 215 - 234

PubMed ID

  • 6975862

International Standard Serial Number (ISSN)

  • 0160-5402

Digital Object Identifier (DOI)

  • 10.1016/0160-5402(81)90089-9


  • eng

Conference Location

  • United States