Pulmonary gas exchange in diving.
Journal Article (Journal Article;Review)
Diving-related pulmonary effects are due mostly to increased gas density, immersion-related increase in pulmonary blood volume, and (usually) a higher inspired Po(2). Higher gas density produces an increase in airways resistance and work of breathing, and a reduced maximum breathing capacity. An additional mechanical load is due to immersion, which can impose a static transrespiratory pressure load as well as a decrease in pulmonary compliance. The combination of resistive and elastic loads is largely responsible for the reduction in ventilation during underwater exercise. Additionally, there is a density-related increase in dead space/tidal volume ratio (Vd/Vt), possibly due to impairment of intrapulmonary gas phase diffusion and distribution of ventilation. The net result of relative hypoventilation and increased Vd/Vt is hypercapnia. The effect of high inspired Po(2) and inert gas narcosis on respiratory drive appear to be minimal. Exchange of oxygen by the lung is not impaired, at least up to a gas density of 25 g/l. There are few effects of pressure per se, other than a reduction in the P50 of hemoglobin, probably due to either a conformational change or an effect of inert gas binding.
Full Text
Duke Authors
Cited Authors
- Moon, RE; Cherry, AD; Stolp, BW; Camporesi, EM
Published Date
- February 2009
Published In
Volume / Issue
- 106 / 2
Start / End Page
- 668 - 677
PubMed ID
- 19008484
International Standard Serial Number (ISSN)
- 8750-7587
Digital Object Identifier (DOI)
- 10.1152/japplphysiol.91104.2008
Language
- eng
Conference Location
- United States