Skip to main content
Journal cover image

FLASH: a rapid method for prototyping paper-based microfluidic devices.

Publication ,  Journal Article
Martinez, AW; Phillips, ST; Wiley, BJ; Gupta, M; Whitesides, GM
Published in: Lab on a chip
December 2008

This article describes FLASH (Fast Lithographic Activation of Sheets), a rapid method for laboratory prototyping of microfluidic devices in paper. Paper-based microfluidic devices are emerging as a new technology for applications in diagnostics for the developing world, where low cost and simplicity are essential. FLASH is based on photolithography, but requires only a UV lamp and a hotplate; no clean-room or special facilities are required (FLASH patterning can even be performed in sunlight if a UV lamp and hotplate are unavailable). The method provides channels in paper with dimensions as small as 200 microm in width and 70 microm in height; the height is defined by the thickness of the paper. Photomasks for patterning paper-based microfluidic devices can be printed using an ink-jet printer or photocopier, or drawn by hand using a waterproof black pen. FLASH provides a straightforward method for prototyping paper-based microfluidic devices in regions where the technological support for conventional photolithography is not available.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Lab on a chip

DOI

EISSN

1473-0189

ISSN

1473-0197

Publication Date

December 2008

Volume

8

Issue

12

Start / End Page

2146 / 2150

Related Subject Headings

  • Time Factors
  • Surface Properties
  • Paper
  • Microfluidics
  • Analytical Chemistry
  • 40 Engineering
  • 34 Chemical sciences
  • 09 Engineering
  • 03 Chemical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Martinez, A. W., Phillips, S. T., Wiley, B. J., Gupta, M., & Whitesides, G. M. (2008). FLASH: a rapid method for prototyping paper-based microfluidic devices. Lab on a Chip, 8(12), 2146–2150. https://doi.org/10.1039/b811135a
Martinez, Andres W., Scott T. Phillips, Benjamin J. Wiley, Malancha Gupta, and George M. Whitesides. “FLASH: a rapid method for prototyping paper-based microfluidic devices.Lab on a Chip 8, no. 12 (December 2008): 2146–50. https://doi.org/10.1039/b811135a.
Martinez AW, Phillips ST, Wiley BJ, Gupta M, Whitesides GM. FLASH: a rapid method for prototyping paper-based microfluidic devices. Lab on a chip. 2008 Dec;8(12):2146–50.
Martinez, Andres W., et al. “FLASH: a rapid method for prototyping paper-based microfluidic devices.Lab on a Chip, vol. 8, no. 12, Dec. 2008, pp. 2146–50. Epmc, doi:10.1039/b811135a.
Martinez AW, Phillips ST, Wiley BJ, Gupta M, Whitesides GM. FLASH: a rapid method for prototyping paper-based microfluidic devices. Lab on a chip. 2008 Dec;8(12):2146–2150.
Journal cover image

Published In

Lab on a chip

DOI

EISSN

1473-0189

ISSN

1473-0197

Publication Date

December 2008

Volume

8

Issue

12

Start / End Page

2146 / 2150

Related Subject Headings

  • Time Factors
  • Surface Properties
  • Paper
  • Microfluidics
  • Analytical Chemistry
  • 40 Engineering
  • 34 Chemical sciences
  • 09 Engineering
  • 03 Chemical Sciences