FLASH: a rapid method for prototyping paper-based microfluidic devices.
Published
Journal Article
This article describes FLASH (Fast Lithographic Activation of Sheets), a rapid method for laboratory prototyping of microfluidic devices in paper. Paper-based microfluidic devices are emerging as a new technology for applications in diagnostics for the developing world, where low cost and simplicity are essential. FLASH is based on photolithography, but requires only a UV lamp and a hotplate; no clean-room or special facilities are required (FLASH patterning can even be performed in sunlight if a UV lamp and hotplate are unavailable). The method provides channels in paper with dimensions as small as 200 microm in width and 70 microm in height; the height is defined by the thickness of the paper. Photomasks for patterning paper-based microfluidic devices can be printed using an ink-jet printer or photocopier, or drawn by hand using a waterproof black pen. FLASH provides a straightforward method for prototyping paper-based microfluidic devices in regions where the technological support for conventional photolithography is not available.
Full Text
Duke Authors
Cited Authors
- Martinez, AW; Phillips, ST; Wiley, BJ; Gupta, M; Whitesides, GM
Published Date
- December 2008
Published In
Volume / Issue
- 8 / 12
Start / End Page
- 2146 - 2150
PubMed ID
- 19023478
Pubmed Central ID
- 19023478
Electronic International Standard Serial Number (EISSN)
- 1473-0189
International Standard Serial Number (ISSN)
- 1473-0197
Digital Object Identifier (DOI)
- 10.1039/b811135a
Language
- eng