The use of cultured Schwann cells in nerve repair in a rabbit hind-limb model.
Publication
, Journal Article
Brown, RE; Erdmann, D; Lyons, SF; Suchy, H
Published in: J Reconstr Microsurg
April 1996
A 3-cm peripheral nerve gap in a rabbit hind-limb model was repaired by using a polyglycolic acid (PGA) conduit filled with a gelatin/Schwann-cell suspension. Postoperative nerve function after 16 weeks, as measured by isometric twitch and tetanic muscle strengths, and nerve conduction velocities, failed to demonstrate a statistically significant difference, compared to a control group in which the nerve gap was reconstructed by using a PGA conduit filled with gelatin only. The 3-cm gap in the described model may not have been long enough to show a significant difference between the two groups. Alternatively, the transferred cultured Schwann cells may have been functionally inactive.
Duke Scholars
Published In
J Reconstr Microsurg
DOI
ISSN
0743-684X
Publication Date
April 1996
Volume
12
Issue
3
Start / End Page
149 / 152
Location
United States
Related Subject Headings
- Surgery
- Schwann Cells
- Rabbits
- Polyglycolic Acid
- Peroneal Nerve
- Neural Conduction
- Nerve Regeneration
- Muscle, Skeletal
- Isometric Contraction
- Hindlimb
Citation
APA
Chicago
ICMJE
MLA
NLM
Brown, R. E., Erdmann, D., Lyons, S. F., & Suchy, H. (1996). The use of cultured Schwann cells in nerve repair in a rabbit hind-limb model. J Reconstr Microsurg, 12(3), 149–152. https://doi.org/10.1055/s-2007-1006468
Brown, R. E., D. Erdmann, S. F. Lyons, and H. Suchy. “The use of cultured Schwann cells in nerve repair in a rabbit hind-limb model.” J Reconstr Microsurg 12, no. 3 (April 1996): 149–52. https://doi.org/10.1055/s-2007-1006468.
Brown RE, Erdmann D, Lyons SF, Suchy H. The use of cultured Schwann cells in nerve repair in a rabbit hind-limb model. J Reconstr Microsurg. 1996 Apr;12(3):149–52.
Brown, R. E., et al. “The use of cultured Schwann cells in nerve repair in a rabbit hind-limb model.” J Reconstr Microsurg, vol. 12, no. 3, Apr. 1996, pp. 149–52. Pubmed, doi:10.1055/s-2007-1006468.
Brown RE, Erdmann D, Lyons SF, Suchy H. The use of cultured Schwann cells in nerve repair in a rabbit hind-limb model. J Reconstr Microsurg. 1996 Apr;12(3):149–152.
Published In
J Reconstr Microsurg
DOI
ISSN
0743-684X
Publication Date
April 1996
Volume
12
Issue
3
Start / End Page
149 / 152
Location
United States
Related Subject Headings
- Surgery
- Schwann Cells
- Rabbits
- Polyglycolic Acid
- Peroneal Nerve
- Neural Conduction
- Nerve Regeneration
- Muscle, Skeletal
- Isometric Contraction
- Hindlimb