Ehrlichiosis in children.


Journal Article (Review)

Ehrlichia are obligate intracellular bacteria that belong to the family Rickettsiaceae. Human monocytic ehrlichiosis (HME) and human granulocytic ehrlichiosis (HGE) are the 2 ehrlichial diseases that are of greatest health concern in the United States. The agents causing HME and HGE are zoonotic pathogens requiring a mammalian reservoir and an arthropod vector. Differences in the geographic distribution of their tick vectors account for the concentration of HME in the South and southeastern United States and HGE in the Northeast and northern Midwest. Both infections have been reported in coastal regions from Rhode Island to Florida. HME and HGE are flulike illnesses that usually are self-limited but may be fatal. Diagnosis is confirmed by identification of the microorganism on blood smear or polymerase chain reaction or by detection of anti-ehrlichial antibody. Doxycycline is the antibiotic of choice for treatment of ehrlichiosis.

Full Text

Duke Authors

Cited Authors

  • Lantos, PM; Krause, PJ

Published Date

  • October 2002

Published In

Volume / Issue

  • 13 / 4

Start / End Page

  • 249 - 256

PubMed ID

  • 12491230

Pubmed Central ID

  • 12491230

International Standard Serial Number (ISSN)

  • 1045-1870

Digital Object Identifier (DOI)

  • 10.1053/spid.2002.127200


  • eng

Conference Location

  • United States