Idiopathic intracranial hypertension: a case report with optic nerve histopathology.


Journal Article (Academic article)

We present the clinical and pathologic findings in an atypical case of idiopathic intracranial hypertension. A 51-year-old man had headaches, visual deterioration, papilloedema, and deafness. Neuroimaging was normal, and cerebrospinal fluid pressure monitoring confirmed increased intracranial pressure. The patient was treated with a ventriculo-peritoneal shunt. Histopathology revealed grossly atrophic optic nerves with almost complete axonal loss. The prelaminar portion of the optic nerves was thickened by gliosis and hyalinized capillaries, which have not been described previously.

Duke Authors

Cited Authors

  • Horgan, HC; McFadzean, RM; Lee, WR

Published Date

  • September 1999

Published In

Volume / Issue

  • 19 / 3

Start / End Page

  • 182 - 185

International Standard Serial Number (ISSN)

  • 1070-8022

Conference Location

  • united states