Pleomorphic fibroma of the eyelid.
Journal Article
BACKGROUND:This report describes the pathology of an unusual variant of fibroma of the eyelid. The soft ovoid tumour was excised from the centre of the left lower lid in an 84-year-old patient had been growing slowly for several years. METHODS:The tumour was studied by conventional histology, immunohistochemistry and electron microscopy. RESULTS:The tumor was formed by fibroblasts of spindle and multinucleate type, and the collagenous stroma contained mast cells and blood vessels which exhibited minor inflammatory changes. With the immunohistochemical methods the only positive marker was for vimentin. CONCLUSION:On morphological grounds it was possible to distinguish this extremely rare tumour from other mesenchymal tumours. The presence of distinctive multinucleate giant cells makes the term pleomorphic fibroma an appropriate name for this type of lesion.
Full Text
Duke Authors
Cited Authors
- Sandinha, T; Lee, WR; Reid, R
Published Date
- May 1998
Published In
Volume / Issue
- 236 / 5
Start / End Page
- 333 - 338
PubMed ID
- 9602316
Pubmed Central ID
- 9602316
Electronic International Standard Serial Number (EISSN)
- 1435-702X
International Standard Serial Number (ISSN)
- 0721-832X
Digital Object Identifier (DOI)
- 10.1007/s004170050087
Language
- eng