Myolipoma of the eyelid.
BACKGROUND: This report describes the pathology of a myolipoma which occurred in the eyelid. Myolipoma is a benign hamartomatous tumour in which smooth muscle cells are interspersed with adipocytes. PATIENT DETAILS: An irregular yellowish tumour (30 x 25 mm) with illdefined borders had been present for 50 years in the medial part of the left lower eyelid of a 67-year-old woman. The tumour was excised and studied by conventional histology, immunohistochemistry and transmission electron microscopy. RESULTS: The tumour was formed by bundles of spindle-shaped cells with cigarshaped nuclei intermingled with multiloculated clear cells containing small eccentric nuclei. By immunohistochemistry, positive staining of the spindle cells was restricted to smooth muscle actin and desmin; the clear cells were non-reactive with the immunohistochemical panel, but fat was identified within the cytoplasm. The ultrastructural features of the spindle cells were those of a leiomyoma, while the clear cells were classified as adipocytes. CONCLUSION: This tumour was considered to originate from the media of blood vessels within the tumour.
Duke Scholars
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Related Subject Headings
- Spindle Apparatus
- Ophthalmology & Optometry
- Muscle, Smooth
- Mucin-1
- Lipoma
- Intermediate Filament Proteins
- Immunohistochemistry
- Humans
- Female
- Eyelid Neoplasms
Citation
Published In
DOI
ISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Spindle Apparatus
- Ophthalmology & Optometry
- Muscle, Smooth
- Mucin-1
- Lipoma
- Intermediate Filament Proteins
- Immunohistochemistry
- Humans
- Female
- Eyelid Neoplasms