Extreme hypofractionation for prostate cancer.
Publication
, Journal Article
Lee, WR
Published in: Expert Rev Anticancer Ther
January 2009
In ideal circumstances the fractionation schedule of radiotherapy should match the fractionation sensitivity of the tumor relative to the nearby normal tissues. A number of recent publications have suggested that the alpha/beta ratio for prostate tumors is low - in the range of 1-3 Gy. In fact, if alpha/beta is low, then hypofractionated schedules using fewer, larger fractions should improve the therapeutic ratio. This critical article examines two methods that represent schedules at the extreme end of the fractionation spectrum (3-5 fractions): high-dose-rate brachytherapy as monotherapy and stereotactic body radiotherapy.
Duke Scholars
Published In
Expert Rev Anticancer Ther
DOI
EISSN
1744-8328
Publication Date
January 2009
Volume
9
Issue
1
Start / End Page
61 / 65
Location
England
Related Subject Headings
- Prostatic Neoplasms
- Oncology & Carcinogenesis
- Middle Aged
- Male
- Humans
- Dose-Response Relationship, Radiation
- Dose Fractionation, Radiation
- Aged
- 3211 Oncology and carcinogenesis
- 1112 Oncology and Carcinogenesis
Citation
APA
Chicago
ICMJE
MLA
NLM
Lee, W. R. (2009). Extreme hypofractionation for prostate cancer. Expert Rev Anticancer Ther, 9(1), 61–65. https://doi.org/10.1586/14737140.9.1.61
Lee, W Robert. “Extreme hypofractionation for prostate cancer.” Expert Rev Anticancer Ther 9, no. 1 (January 2009): 61–65. https://doi.org/10.1586/14737140.9.1.61.
Lee WR. Extreme hypofractionation for prostate cancer. Expert Rev Anticancer Ther. 2009 Jan;9(1):61–5.
Lee, W. Robert. “Extreme hypofractionation for prostate cancer.” Expert Rev Anticancer Ther, vol. 9, no. 1, Jan. 2009, pp. 61–65. Pubmed, doi:10.1586/14737140.9.1.61.
Lee WR. Extreme hypofractionation for prostate cancer. Expert Rev Anticancer Ther. 2009 Jan;9(1):61–65.
Published In
Expert Rev Anticancer Ther
DOI
EISSN
1744-8328
Publication Date
January 2009
Volume
9
Issue
1
Start / End Page
61 / 65
Location
England
Related Subject Headings
- Prostatic Neoplasms
- Oncology & Carcinogenesis
- Middle Aged
- Male
- Humans
- Dose-Response Relationship, Radiation
- Dose Fractionation, Radiation
- Aged
- 3211 Oncology and carcinogenesis
- 1112 Oncology and Carcinogenesis