Hyponatremia treatment guidelines 2007: expert panel recommendations.
Journal Article (Journal Article)
Although hyponatremia is a common, usually mild, and relatively asymptomatic disorder of electrolytes, acute severe hyponatremia can cause substantial morbidity and mortality, particularly in patients with concomitant disease. In addition, overly rapid correction of chronic hyponatremia can cause severe neurologic deficits and death, and optimal treatment strategies for such cases are not established. An expert panel assessed the potential contributions of aquaretic nonpeptide small-molecule arginine vasopressin receptor (AVPR) antagonists to hyponatremia therapies. This review presents their conclusions, including identification of appropriate treatment populations and possible future indications for aquaretic AVPR antagonists.
Full Text
Duke Authors
Cited Authors
- Verbalis, JG; Goldsmith, SR; Greenberg, A; Schrier, RW; Sterns, RH
Published Date
- November 2007
Published In
Volume / Issue
- 120 / 11 Suppl 1
Start / End Page
- S1 - 21
PubMed ID
- 17981159
Pubmed Central ID
- 17981159
Electronic International Standard Serial Number (EISSN)
- 1555-7162
Digital Object Identifier (DOI)
- 10.1016/j.amjmed.2007.09.001
Language
- eng
Conference Location
- United States