Health care costs in the last week of life: associations with end-of-life conversations.

Journal Article (Journal Article)

BACKGROUND: Life-sustaining medical care of patients with advanced cancer at the end of life (EOL) is costly. Patient-physician discussions about EOL wishes are associated with lower rates of intensive interventions. METHODS: Funded by the National Institute of Mental Health and the National Cancer Institute, Coping With Cancer is a longitudinal multi-institutional study of 627 patients with advanced cancer. Patients were interviewed at baseline and were followed up through death. Costs for intensive care unit and hospital stays, hospice care, and life-sustaining procedures (eg, mechanical ventilator use and resuscitation) received in the last week of life were aggregated. Generalized linear models were applied to test for cost differences in EOL care. Propensity score matching was used to reduce selection biases. RESULTS: Of 603 participants, 188 (31.2%) reported EOL discussions at baseline. After propensity score matching, the remaining 415 patients did not differ in sociodemographic characteristics, recruitment sites, illness acknowledgment, or treatment preferences. Further analyses, adjusted by quintiles of propensity scores and significant confounders, revealed that the mean (SE) aggregate costs of care (in 2008 US dollars) were $1876 ($177) for patients who reported EOL discussions compared with $2917 ($285) for patients who did not, a cost difference of $1041 (35.7% lower among patients who reported EOL discussions) (P =.002). Patients with higher costs had worse quality of death in their final week (Pearson production moment correlation partial r = -0.17, P =.006). CONCLUSIONS: Patients with advanced cancer who reported having EOL conversations with physicians had significantly lower health care costs in their final week of life. Higher costs were associated with worse quality of death.

Full Text

Duke Authors

Cited Authors

  • Zhang, B; Wright, AA; Huskamp, HA; Nilsson, ME; Maciejewski, ML; Earle, CC; Block, SD; Maciejewski, PK; Prigerson, HG

Published Date

  • March 9, 2009

Published In

Volume / Issue

  • 169 / 5

Start / End Page

  • 480 - 488

PubMed ID

  • 19273778

Pubmed Central ID

  • PMC2862687

Electronic International Standard Serial Number (EISSN)

  • 1538-3679

Digital Object Identifier (DOI)

  • 10.1001/archinternmed.2008.587


  • eng

Conference Location

  • United States