Effects of procainamide and quinidine sulfate in the Wolff-Parkinson-White syndrome.

Journal Article (Journal Article)

Thirty-three patients with Wolff-Parkinson-White syndrome were studied electrophysiologically before and after administration of intravenous procainamide and oral quinidine sulfate. Procainamide prolonged the shortest R-R (SRR) interval between two consecutive pre-excited beats during atrial fibrillation 20-70 msec in 15 of 21 patients with no change observed in 6 of 21 patients. Quinidine sulfate prolonged the SRR 20-170 msec in all 16. In 14 of 18 patients where procainamide and quinidine were comparable, quinidine prolonged the SRR 30-100 msec more than procainamide.

Full Text

Duke Authors

Cited Authors

  • Sellers, TD; Campbell, RW; Bashore, TM; Gallagher, JJ

Published Date

  • January 1, 1977

Published In

Volume / Issue

  • 55 / 1

Start / End Page

  • 15 - 22

PubMed ID

  • 830205

International Standard Serial Number (ISSN)

  • 0009-7322

Digital Object Identifier (DOI)

  • 10.1161/01.cir.55.1.15


  • eng

Conference Location

  • United States