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Changes in left ventricular diastolic performance after aortic balloon valvuloplasty: acute and late effects.

Publication ,  Journal Article
Sheikh, KH; Davidson, CJ; Honan, MB; Skelton, TN; Kisslo, KB; Bashore, TM
Published in: J Am Coll Cardiol
October 1990

To evaluate acute and follow-up changes in left ventricular diastolic performance, simultaneous digital left ventriculography and micromanometry were performed in 49 patients undergoing aortic balloon valvuloplasty. All patients improved symptomatically after valvuloplasty, and 26 returned 6.3 +/- 1.5 months later for follow-up catheterization. Immediately after valvuloplasty, aortic valve area increased (before 0.5 +/- 0.2 versus after 0.8 +/- 0.2 cm2, p less than 0.01), cardiac output (before 4.3 +/- 1.2 versus after 4.4 +/- 1.3 liters/min) and ejection fraction (before 51 +/- 18% versus after 52 +/- 17%) did not change and diastolic indexes worsened, signified by a decrease in peak filling rate (before 247 +/- 80 versus after 226 +/- 78 ml/s, p less than 0.01) and increase in the time constant of isovolumetric relaxation (tau) (before 78 +/- 29 versus after 96 +/- 40 ms, p less than 0.01) and the modulus of chamber stiffness (before 0.107 +/- 0.071 versus after 0.141 +/- 0.083, p less than 0.01). At follow-up catheterization, 16 patients continued to have symptomatic improvement (group 1) and 10 had recurrence of symptoms (group 2). Aortic valve area, cardiac output and ejection fraction at follow-up catheterization in both groups were similar and unchanged from values before valvuloplasty.(ABSTRACT TRUNCATED AT 250 WORDS)

Duke Scholars

Published In

J Am Coll Cardiol

DOI

ISSN

0735-1097

Publication Date

October 1990

Volume

16

Issue

4

Start / End Page

795 / 803

Location

United States

Related Subject Headings

  • Ventricular Function, Left
  • Time Factors
  • Male
  • Humans
  • Heart
  • Gated Blood-Pool Imaging
  • Follow-Up Studies
  • Female
  • Echocardiography
  • Diastole
 

Citation

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Sheikh, K. H., Davidson, C. J., Honan, M. B., Skelton, T. N., Kisslo, K. B., & Bashore, T. M. (1990). Changes in left ventricular diastolic performance after aortic balloon valvuloplasty: acute and late effects. J Am Coll Cardiol, 16(4), 795–803. https://doi.org/10.1016/s0735-1097(10)80324-9
Sheikh, K. H., C. J. Davidson, M. B. Honan, T. N. Skelton, K. B. Kisslo, and T. M. Bashore. “Changes in left ventricular diastolic performance after aortic balloon valvuloplasty: acute and late effects.J Am Coll Cardiol 16, no. 4 (October 1990): 795–803. https://doi.org/10.1016/s0735-1097(10)80324-9.
Sheikh KH, Davidson CJ, Honan MB, Skelton TN, Kisslo KB, Bashore TM. Changes in left ventricular diastolic performance after aortic balloon valvuloplasty: acute and late effects. J Am Coll Cardiol. 1990 Oct;16(4):795–803.
Sheikh, K. H., et al. “Changes in left ventricular diastolic performance after aortic balloon valvuloplasty: acute and late effects.J Am Coll Cardiol, vol. 16, no. 4, Oct. 1990, pp. 795–803. Pubmed, doi:10.1016/s0735-1097(10)80324-9.
Sheikh KH, Davidson CJ, Honan MB, Skelton TN, Kisslo KB, Bashore TM. Changes in left ventricular diastolic performance after aortic balloon valvuloplasty: acute and late effects. J Am Coll Cardiol. 1990 Oct;16(4):795–803.
Journal cover image

Published In

J Am Coll Cardiol

DOI

ISSN

0735-1097

Publication Date

October 1990

Volume

16

Issue

4

Start / End Page

795 / 803

Location

United States

Related Subject Headings

  • Ventricular Function, Left
  • Time Factors
  • Male
  • Humans
  • Heart
  • Gated Blood-Pool Imaging
  • Follow-Up Studies
  • Female
  • Echocardiography
  • Diastole