Skip to main content
Journal cover image

Hemodynamic correlates for timing intervals, ejection rate and filling rate derived from the radionuclide angiographic volume curve.

Publication ,  Journal Article
Magorien, DJ; Shaffer, P; Bush, C; Magorien, RD; Kolibash, AJ; Unverferth, DV; Bashore, TM
Published in: Am J Cardiol
February 1, 1984

This study was designed to more clearly define the relation between various invasive hemodynamic measurements and left ventricular (LV) timing intervals, ejection rate and filling rate derived from the radionuclide angiographic volume curve. Twenty-eight patients were studied with simultaneous intracardiac micromanometer pressure and dP/dt recordings, gated radionuclide angiography and M-mode echocardiography. These techniques permitted multiple variables of systolic and diastolic function to be measured at a constant atrial paced rate of 100 beats/min. There was a strong correlation between peak ejection rate and ejection fraction (r = -0.97) and between peak ejection rate and maximum positive dP/dt (r = -0.85). There also was a strong correlation between peak filling rate and maximum negative dP/dt (r = -0.85). A weaker correlation existed between the time constant of LV relaxation and the peak filling rate (r = -0.49) and between the LV end-diastolic pressure and the peak filling rate (r = -0.62). There was no correlation between the modulus of chamber stiffness and filling rates, and no association was observed between the time to peak filling rate and the hemodynamic variables. Thus, under the conditions studied, the measured peak ejection and filling rate, determined from the radionuclide angiographic volume curve, correlated well with accepted invasive hemodynamic measurements.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Am J Cardiol

DOI

ISSN

0002-9149

Publication Date

February 1, 1984

Volume

53

Issue

4

Start / End Page

567 / 571

Location

United States

Related Subject Headings

  • Time Factors
  • Technetium
  • Stroke Volume
  • Sodium Pertechnetate Tc 99m
  • Radionuclide Imaging
  • Myocardial Contraction
  • Middle Aged
  • Manometry
  • Male
  • Humans
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Magorien, D. J., Shaffer, P., Bush, C., Magorien, R. D., Kolibash, A. J., Unverferth, D. V., & Bashore, T. M. (1984). Hemodynamic correlates for timing intervals, ejection rate and filling rate derived from the radionuclide angiographic volume curve. Am J Cardiol, 53(4), 567–571. https://doi.org/10.1016/0002-9149(84)90032-8
Magorien, D. J., P. Shaffer, C. Bush, R. D. Magorien, A. J. Kolibash, D. V. Unverferth, and T. M. Bashore. “Hemodynamic correlates for timing intervals, ejection rate and filling rate derived from the radionuclide angiographic volume curve.Am J Cardiol 53, no. 4 (February 1, 1984): 567–71. https://doi.org/10.1016/0002-9149(84)90032-8.
Magorien DJ, Shaffer P, Bush C, Magorien RD, Kolibash AJ, Unverferth DV, et al. Hemodynamic correlates for timing intervals, ejection rate and filling rate derived from the radionuclide angiographic volume curve. Am J Cardiol. 1984 Feb 1;53(4):567–71.
Magorien, D. J., et al. “Hemodynamic correlates for timing intervals, ejection rate and filling rate derived from the radionuclide angiographic volume curve.Am J Cardiol, vol. 53, no. 4, Feb. 1984, pp. 567–71. Pubmed, doi:10.1016/0002-9149(84)90032-8.
Magorien DJ, Shaffer P, Bush C, Magorien RD, Kolibash AJ, Unverferth DV, Bashore TM. Hemodynamic correlates for timing intervals, ejection rate and filling rate derived from the radionuclide angiographic volume curve. Am J Cardiol. 1984 Feb 1;53(4):567–571.
Journal cover image

Published In

Am J Cardiol

DOI

ISSN

0002-9149

Publication Date

February 1, 1984

Volume

53

Issue

4

Start / End Page

567 / 571

Location

United States

Related Subject Headings

  • Time Factors
  • Technetium
  • Stroke Volume
  • Sodium Pertechnetate Tc 99m
  • Radionuclide Imaging
  • Myocardial Contraction
  • Middle Aged
  • Manometry
  • Male
  • Humans