Foveal hypoplasia in oculocutaneous albinism demonstrated by optical coherence tomography.

Journal Article (Journal Article)

PURPOSE: To document, in vivo, the foveal morphology and thickness in a patient with oculocutaneous albinism. METHODS: Observational case report. In a 10-year-old female with oculocutaneous albinism, multiple cross-sectional scans of the fovea were performed using optical coherence tomography. RESULTS: Optical coherence tomography scans were unable to detect the foveal pit. A widespread thickening of the retina occurred throughout the entire fovea with no difference from the surrounding macula. The foveal thickness was greater than 300 microm in the eyes of this patient with oculocutaneous albinism, compared with 150 microm in the normal eye. The inner retina had a highly reflective signal on optical coherence tomography. CONCLUSION: Optical coherence tomography demonstrated in the anatomical location of the fovea a highly reflective inner retinal signal, possibly consistent with multiple layers of ganglion cells, and it confirmed foveal hypoplasia in a patient with oculocutaneous albinism.

Full Text

Duke Authors

Cited Authors

  • Meyer, CH; Lapolice, DJ; Freedman, SF

Published Date

  • March 2002

Published In

Volume / Issue

  • 133 / 3

Start / End Page

  • 409 - 410

PubMed ID

  • 11860983

International Standard Serial Number (ISSN)

  • 0002-9394

Digital Object Identifier (DOI)

  • 10.1016/s0002-9394(01)01326-5


  • eng

Conference Location

  • United States