A health services research agenda for cellular, molecular and genomic technologies in cancer care.


Journal Article (Review)

BACKGROUND:In recent decades, extensive resources have been invested to develop cellular, molecular and genomic technologies with clinical applications that span the continuum of cancer care. METHODS:In December 2006, the National Cancer Institute sponsored the first workshop to uniquely examine the state of health services research on cancer-related cellular, molecular and genomic technologies and identify challenges and priorities for expanding the evidence base on their effectiveness in routine care. RESULTS:This article summarizes the workshop outcomes, which included development of a comprehensive research agenda that incorporates health and safety endpoints, utilization patterns, patient and provider preferences, quality of care and access, disparities, economics and decision modeling, trends in cancer outcomes, and health-related quality of life among target populations. CONCLUSIONS:Ultimately, the successful adoption of useful technologies will depend on understanding and influencing the patient, provider, health care system and societal factors that contribute to their uptake and effectiveness in 'real-world' settings.

Full Text

Cited Authors

  • Wideroff, L; Phillips, KA; Randhawa, G; Ambs, A; Armstrong, K; Bennett, CL; Brown, ML; Donaldson, MS; Follen, M; Goldie, SJ; Hiatt, RA; Khoury, MJ; Lewis, G; McLeod, HL; Piper, M; Powell, I; Schrag, D; Schulman, KA; Scott, J

Published Date

  • January 2009

Published In

Volume / Issue

  • 12 / 4

Start / End Page

  • 233 - 244

PubMed ID

  • 19367091

Pubmed Central ID

  • 19367091

Electronic International Standard Serial Number (EISSN)

  • 1662-8063

International Standard Serial Number (ISSN)

  • 1662-4246

Digital Object Identifier (DOI)

  • 10.1159/000203779


  • eng