Analysis of nonylphenol and nonylphenol ethoxylates in environmental samples by mixed-mode high-performance liquid chromatography-electrospray mass spectrometry.

Journal Article (Journal Article)

A new method is described based on mixed-mode high-performance liquid chromatography with electrospray mass spectrometry detection for comprehensive quantitative analysis of nonylphenol (NP) and nonylphenol ethoxylates (NPEOs) in wastewater and sediment. Efficient separation, reduced band broadening, and high sensitivity were achieved by employing a methanol-water gradient on a mixed-solvent gel filtration column designed for MS interfacing. Quantitative accuracy and precision of the method were improved by the use of custom-synthesized [13C6]NPEO analogs as isotope-dilution surrogate standards. Method detection limits for NP and individual NPEOs ranged from I to 55 pg injected on column.

Full Text

Duke Authors

Cited Authors

  • Ferguson, PL; Iden, CR; Brownawel, BJ

Published Date

  • December 2001

Published In

Volume / Issue

  • 938 / 1-2

Start / End Page

  • 79 - 91

PubMed ID

  • 11771849

Electronic International Standard Serial Number (EISSN)

  • 1873-3778

International Standard Serial Number (ISSN)

  • 0021-9673

Digital Object Identifier (DOI)

  • 10.1016/s0021-9673(01)01091-3


  • eng