Skip to main content
Journal cover image

Single-dose captopril scintigraphy in the neonate with renovascular hypertension: prediction of renal failure, a side effect of captopril therapy.

Publication ,  Journal Article
Sfakianakis, GN; Sfakianaki, E; Paredes, A; Abitbol, C; Zilleruelo, G; Goldberg, RN; Strauss, J
Published in: Biol Neonate
1988

Baseline and single-dose captopril scintigraphy with 1 mCi of 99mTc-diethylenetriamine-pentaacetic acid (or 99mTc-glucoheptonate) was performed in 5 neonates with renovascular hypertension. Unilateral renal artery thrombosis and/or renal infarction was associated with severe impairment or lack of function on both studies (3 patients). Renal ischemia due to aortic thrombus manifested itself as lack of function only following captopril (2 patients). This approach predicted renal failure as a side effect of captopril therapy in 2 patients, 1 with unilateral (contralateral kidney infarcted) and the other with bilateral renal ischemia from aortic thrombus. Single-dose captopril scintigraphy may be a useful tool to predict tolerance to captopril therapy.

Duke Scholars

Published In

Biol Neonate

DOI

ISSN

0006-3126

Publication Date

1988

Volume

54

Issue

5

Start / End Page

246 / 253

Location

Switzerland

Related Subject Headings

  • Umbilical Arteries
  • Ultrasonics
  • Radionuclide Imaging
  • Pediatrics
  • Male
  • Kidney
  • Infant, Newborn
  • Hypertension, Renovascular
  • Humans
  • Female
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Sfakianakis, G. N., Sfakianaki, E., Paredes, A., Abitbol, C., Zilleruelo, G., Goldberg, R. N., & Strauss, J. (1988). Single-dose captopril scintigraphy in the neonate with renovascular hypertension: prediction of renal failure, a side effect of captopril therapy. Biol Neonate, 54(5), 246–253. https://doi.org/10.1159/000242859
Sfakianakis, G. N., E. Sfakianaki, A. Paredes, C. Abitbol, G. Zilleruelo, R. N. Goldberg, and J. Strauss. “Single-dose captopril scintigraphy in the neonate with renovascular hypertension: prediction of renal failure, a side effect of captopril therapy.Biol Neonate 54, no. 5 (1988): 246–53. https://doi.org/10.1159/000242859.
Sfakianakis GN, Sfakianaki E, Paredes A, Abitbol C, Zilleruelo G, Goldberg RN, et al. Single-dose captopril scintigraphy in the neonate with renovascular hypertension: prediction of renal failure, a side effect of captopril therapy. Biol Neonate. 1988;54(5):246–53.
Sfakianakis, G. N., et al. “Single-dose captopril scintigraphy in the neonate with renovascular hypertension: prediction of renal failure, a side effect of captopril therapy.Biol Neonate, vol. 54, no. 5, 1988, pp. 246–53. Pubmed, doi:10.1159/000242859.
Sfakianakis GN, Sfakianaki E, Paredes A, Abitbol C, Zilleruelo G, Goldberg RN, Strauss J. Single-dose captopril scintigraphy in the neonate with renovascular hypertension: prediction of renal failure, a side effect of captopril therapy. Biol Neonate. 1988;54(5):246–253.
Journal cover image

Published In

Biol Neonate

DOI

ISSN

0006-3126

Publication Date

1988

Volume

54

Issue

5

Start / End Page

246 / 253

Location

Switzerland

Related Subject Headings

  • Umbilical Arteries
  • Ultrasonics
  • Radionuclide Imaging
  • Pediatrics
  • Male
  • Kidney
  • Infant, Newborn
  • Hypertension, Renovascular
  • Humans
  • Female