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Dynamic change of fecal calprotectin in very low birth weight infants during the first month of life.

Publication ,  Journal Article
Yang, Q; Smith, PB; Goldberg, RN; Cotten, CM
Published in: Neonatology
2008

BACKGROUND: Calprotectin is a cytosolic component of neutrophils. Fecal calprotectin (FC) level is a useful marker for exacerbation of inflammatory bowel disease in children. FC may be a useful marker for necrotizing enterocolitis (NEC). OBJECTIVE: To determine normal baseline levels of FC and observe dynamic changes of FC levels over the first postnatal month in very low birth weight (VLBW) infants. METHODS: FC levels of 14 VLBW infants (gestational age 23-30 weeks, birth weight 350 microg/g stool was noted with signs of gastrointestinal injury, such as bloody stool and bowel perforation. FC levels decreased after initiation of treatments in sick infants who recovered. CONCLUSIONS: FC levels may be a marker for early diagnosis and resolution of gastrointestinal illnesses in VLBW infants. Its utility for early diagnosis and assessment of resolution of NEC should be studied in a larger cohort of VLBW infants.

Duke Scholars

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Published In

Neonatology

DOI

EISSN

1661-7819

Publication Date

2008

Volume

94

Issue

4

Start / End Page

267 / 271

Location

Switzerland

Related Subject Headings

  • Prospective Studies
  • Pilot Projects
  • Pediatrics
  • Male
  • Leukocyte L1 Antigen Complex
  • Infant, Very Low Birth Weight
  • Infant, Newborn
  • Humans
  • Female
  • Feces
 

Citation

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Yang, Q., Smith, P. B., Goldberg, R. N., & Cotten, C. M. (2008). Dynamic change of fecal calprotectin in very low birth weight infants during the first month of life. Neonatology, 94(4), 267–271. https://doi.org/10.1159/000151645
Yang, Qing, P Brian Smith, Ronald N. Goldberg, and C Michael Cotten. “Dynamic change of fecal calprotectin in very low birth weight infants during the first month of life.Neonatology 94, no. 4 (2008): 267–71. https://doi.org/10.1159/000151645.
Yang Q, Smith PB, Goldberg RN, Cotten CM. Dynamic change of fecal calprotectin in very low birth weight infants during the first month of life. Neonatology. 2008;94(4):267–71.
Yang, Qing, et al. “Dynamic change of fecal calprotectin in very low birth weight infants during the first month of life.Neonatology, vol. 94, no. 4, 2008, pp. 267–71. Pubmed, doi:10.1159/000151645.
Yang Q, Smith PB, Goldberg RN, Cotten CM. Dynamic change of fecal calprotectin in very low birth weight infants during the first month of life. Neonatology. 2008;94(4):267–271.
Journal cover image

Published In

Neonatology

DOI

EISSN

1661-7819

Publication Date

2008

Volume

94

Issue

4

Start / End Page

267 / 271

Location

Switzerland

Related Subject Headings

  • Prospective Studies
  • Pilot Projects
  • Pediatrics
  • Male
  • Leukocyte L1 Antigen Complex
  • Infant, Very Low Birth Weight
  • Infant, Newborn
  • Humans
  • Female
  • Feces