Advancing high-throughput gene synthesis technology.


Journal Article (Review)

The emerging field of synthetic biology is generating insatiable demands for synthetic genes, which far exceed existing gene synthesis capabilities. This review discusses the current methods of chemical DNA synthesis and gene assembly, as well as the latest engineering tools, technologies and trends which could potentially lead to breakthroughs in the development of accurate, low-cost and high-throughput gene synthesis technology. The capability of generating unlimited supplies of DNA molecules of any sequence or size will transform biomedical research in the near future.

Full Text

Cited Authors

  • Tian, J; Ma, K; Saaem, I

Published Date

  • July 2009

Published In

Volume / Issue

  • 5 / 7

Start / End Page

  • 714 - 722

PubMed ID

  • 19562110

Pubmed Central ID

  • 19562110

Electronic International Standard Serial Number (EISSN)

  • 1742-2051

International Standard Serial Number (ISSN)

  • 1742-206X

Digital Object Identifier (DOI)

  • 10.1039/b822268c


  • eng