Advancing high-throughput gene synthesis technology.
Publication
, Journal Article
Tian, J; Ma, K; Saaem, I
Published in: Molecular bioSystems
July 2009
The emerging field of synthetic biology is generating insatiable demands for synthetic genes, which far exceed existing gene synthesis capabilities. This review discusses the current methods of chemical DNA synthesis and gene assembly, as well as the latest engineering tools, technologies and trends which could potentially lead to breakthroughs in the development of accurate, low-cost and high-throughput gene synthesis technology. The capability of generating unlimited supplies of DNA molecules of any sequence or size will transform biomedical research in the near future.
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Published In
Molecular bioSystems
DOI
EISSN
1742-2051
ISSN
1742-206X
Publication Date
July 2009
Volume
5
Issue
7
Start / End Page
714 / 722
Related Subject Headings
- Photochemistry
- Oligonucleotide Array Sequence Analysis
- Microfluidics
- Genetic Engineering
- Genes, Synthetic
- DNA
- Biochemistry & Molecular Biology
- 3101 Biochemistry and cell biology
- 0601 Biochemistry and Cell Biology
Citation
APA
Chicago
ICMJE
MLA
NLM
Tian, J., Ma, K., & Saaem, I. (2009). Advancing high-throughput gene synthesis technology. Molecular BioSystems, 5(7), 714–722. https://doi.org/10.1039/b822268c
Tian, Jingdong, Kuosheng Ma, and Ishtiaq Saaem. “Advancing high-throughput gene synthesis technology.” Molecular BioSystems 5, no. 7 (July 2009): 714–22. https://doi.org/10.1039/b822268c.
Tian J, Ma K, Saaem I. Advancing high-throughput gene synthesis technology. Molecular bioSystems. 2009 Jul;5(7):714–22.
Tian, Jingdong, et al. “Advancing high-throughput gene synthesis technology.” Molecular BioSystems, vol. 5, no. 7, July 2009, pp. 714–22. Epmc, doi:10.1039/b822268c.
Tian J, Ma K, Saaem I. Advancing high-throughput gene synthesis technology. Molecular bioSystems. 2009 Jul;5(7):714–722.
Published In
Molecular bioSystems
DOI
EISSN
1742-2051
ISSN
1742-206X
Publication Date
July 2009
Volume
5
Issue
7
Start / End Page
714 / 722
Related Subject Headings
- Photochemistry
- Oligonucleotide Array Sequence Analysis
- Microfluidics
- Genetic Engineering
- Genes, Synthetic
- DNA
- Biochemistry & Molecular Biology
- 3101 Biochemistry and cell biology
- 0601 Biochemistry and Cell Biology