Inclusion of a sensitivity control to add a quality-control parameter and improve reproducibility in BCR, immunoglobulin, and T-cell receptor gene-rearrangement studies.
Publication
, Journal Article
Devlin, BH; Ratech, H; Kaufman, R
Published in: Diagn Mol Pathol
December 1994
Molecular analyses to determine clonality of T and B cells in malignant lymphoma and leukemia and to detect the (9;22) translocation in chronic myelogenous leukemia are commonly used in clinical molecular biology laboratories. We describe the inclusion of a sensitivity control in each of these assays derived from DNA of well-characterized cell lines. The inclusion of such a sample adds an important quality-control parameter to ensure assay-to-assay reproducibility and to satisfy accreditation and regulatory requirements.
Duke Scholars
Published In
Diagn Mol Pathol
DOI
ISSN
1052-9551
Publication Date
December 1994
Volume
3
Issue
4
Start / End Page
271 / 274
Location
United States
Related Subject Headings
- Tumor Cells, Cultured
- Reproducibility of Results
- Receptors, Antigen, T-Cell
- Receptors, Antigen, B-Cell
- Quality Control
- Philadelphia Chromosome
- Pathology
- Lymphoma
- Immunoglobulins
- Humans
Citation
APA
Chicago
ICMJE
MLA
NLM
Devlin, B. H., Ratech, H., & Kaufman, R. (1994). Inclusion of a sensitivity control to add a quality-control parameter and improve reproducibility in BCR, immunoglobulin, and T-cell receptor gene-rearrangement studies. Diagn Mol Pathol, 3(4), 271–274. https://doi.org/10.1097/00019606-199412000-00010
Devlin, B. H., H. Ratech, and R. Kaufman. “Inclusion of a sensitivity control to add a quality-control parameter and improve reproducibility in BCR, immunoglobulin, and T-cell receptor gene-rearrangement studies.” Diagn Mol Pathol 3, no. 4 (December 1994): 271–74. https://doi.org/10.1097/00019606-199412000-00010.
Devlin BH, Ratech H, Kaufman R. Inclusion of a sensitivity control to add a quality-control parameter and improve reproducibility in BCR, immunoglobulin, and T-cell receptor gene-rearrangement studies. Diagn Mol Pathol. 1994 Dec;3(4):271–4.
Devlin, B. H., et al. “Inclusion of a sensitivity control to add a quality-control parameter and improve reproducibility in BCR, immunoglobulin, and T-cell receptor gene-rearrangement studies.” Diagn Mol Pathol, vol. 3, no. 4, Dec. 1994, pp. 271–74. Pubmed, doi:10.1097/00019606-199412000-00010.
Devlin BH, Ratech H, Kaufman R. Inclusion of a sensitivity control to add a quality-control parameter and improve reproducibility in BCR, immunoglobulin, and T-cell receptor gene-rearrangement studies. Diagn Mol Pathol. 1994 Dec;3(4):271–274.
Published In
Diagn Mol Pathol
DOI
ISSN
1052-9551
Publication Date
December 1994
Volume
3
Issue
4
Start / End Page
271 / 274
Location
United States
Related Subject Headings
- Tumor Cells, Cultured
- Reproducibility of Results
- Receptors, Antigen, T-Cell
- Receptors, Antigen, B-Cell
- Quality Control
- Philadelphia Chromosome
- Pathology
- Lymphoma
- Immunoglobulins
- Humans