Neural misdirection in congenital ocular fibrosis syndrome: implications and pathogenesis.

Journal Article (Journal Article)

A child with congenital ocular fibrosis syndrome and oculocutaneous albinism displayed two distinct neural misdirection syndromes: synergistic divergence and Marcus Gunn jaw winking. This and other reported cases of misdirected innervation in patients with congenital fibrosis syndrome suggest that normal neuronal connections fail to become established early in development and that lack of innervation may underlie the pathologic features of the disorder. The prevailing concept of congenital fibrosis syndrome as a primary myopathy should be reconsidered.

Full Text

Duke Authors

Cited Authors

  • Brodsky, MC; Pollock, SC; Buckley, EG

Published Date

  • July 1, 1989

Published In

Volume / Issue

  • 26 / 4

Start / End Page

  • 159 - 161

PubMed ID

  • 2760786

International Standard Serial Number (ISSN)

  • 0191-3913

Digital Object Identifier (DOI)

  • 10.3928/0191-3913-19890701-03

Language

  • eng

Conference Location

  • United States