125I embedded in an orbital prosthesis for retreatment of recurrent retinoblastoma.

Journal Article (Journal Article)

The application of radiation therapy in the retreatment of unilateral recurrent retinoblastoma presents a very difficult dilemma in which consideration must be given to preservation of vision in the remaining eye while tumoricidal doses of irradiation are delivered. A technique is described in which a methylmetraculate eye sphere carrying a single Iodine-125 seed was used to deliver local irradiation to the orbital tissues in a patient with multiple episodes of recurrent retinoblastoma. The tissue dose at 2 mm depth was 2630 cGy while the dose to the retina of the remaining eye and to the optic chiasm was negligible.

Full Text

Duke Authors

Cited Authors

  • Bentel, GC; Halperin, EC; Buckley, EG

Published Date

  • 1993

Published In

Volume / Issue

  • 18 / 1

Start / End Page

  • 1 - 5

PubMed ID

  • 8507353

International Standard Serial Number (ISSN)

  • 0958-3947

Digital Object Identifier (DOI)

  • 10.1016/0958-3947(93)90019-p


  • eng

Conference Location

  • United States