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"Cracked-mud" ciprofloxacin precipitates on a corneal graft.

Publication ,  Journal Article
Tanhehco, TY; Chiavetta, SV; Lee, PP; Fowler, AM; Afshari, NA
Published in: Ophthalmic Surg Lasers Imaging
2005

The authors describe an extreme case of ciprofloxacin deposition on the corneal graft of a 67-year-old man with a history of penetrating keratoplasty for corneal ulcer and perforation, who presented with dense, gray deposits on the anterior corneal surface after being treated with ciprofloxacin for an epithelial defect. The deposits resolved after ciprofloxacin was discontinued. The non-physiologic pH of the drug formulation is thought to trigger corneal precipitates, and it remains to be seen whether fourth-generation fluoroquinolones will have a lower incidence of ocular precipitates.

Duke Scholars

Published In

Ophthalmic Surg Lasers Imaging

ISSN

1542-8877

Publication Date

2005

Volume

36

Issue

3

Start / End Page

252 / 253

Location

United States

Related Subject Headings

  • Vision Disorders
  • Recurrence
  • Ophthalmology & Optometry
  • Male
  • Hydrogen-Ion Concentration
  • Humans
  • Corneal Transplantation
  • Corneal Diseases
  • Cornea
  • Ciprofloxacin
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Tanhehco, T. Y., Chiavetta, S. V., Lee, P. P., Fowler, A. M., & Afshari, N. A. (2005). "Cracked-mud" ciprofloxacin precipitates on a corneal graft. Ophthalmic Surg Lasers Imaging, 36(3), 252–253.
Tanhehco, Tasha Y., Stephen V. Chiavetta, Paul P. Lee, Amy M. Fowler, and Natalie A. Afshari. “"Cracked-mud" ciprofloxacin precipitates on a corneal graft.Ophthalmic Surg Lasers Imaging 36, no. 3 (2005): 252–53.
Tanhehco TY, Chiavetta SV, Lee PP, Fowler AM, Afshari NA. "Cracked-mud" ciprofloxacin precipitates on a corneal graft. Ophthalmic Surg Lasers Imaging. 2005;36(3):252–3.
Tanhehco, Tasha Y., et al. “"Cracked-mud" ciprofloxacin precipitates on a corneal graft.Ophthalmic Surg Lasers Imaging, vol. 36, no. 3, 2005, pp. 252–53.
Tanhehco TY, Chiavetta SV, Lee PP, Fowler AM, Afshari NA. "Cracked-mud" ciprofloxacin precipitates on a corneal graft. Ophthalmic Surg Lasers Imaging. 2005;36(3):252–253.

Published In

Ophthalmic Surg Lasers Imaging

ISSN

1542-8877

Publication Date

2005

Volume

36

Issue

3

Start / End Page

252 / 253

Location

United States

Related Subject Headings

  • Vision Disorders
  • Recurrence
  • Ophthalmology & Optometry
  • Male
  • Hydrogen-Ion Concentration
  • Humans
  • Corneal Transplantation
  • Corneal Diseases
  • Cornea
  • Ciprofloxacin