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Nonoperative management of non-small cell lung cancer: the current cancer and leukemia group B experience.

Publication ,  Journal Article
Green, MR; Kosty, MP; Muscato, JJ; Graziano, S; Dillman, RO; Clamon, GH; Herndon, J
Published in: Semin Oncol
June 1994

The Cancer and Leukemia Group B (CALGB) is studying nonoperative management in two subgroups of patients with advanced non-small cell lung cancer. In patients with regional disease, primarily those with bulky N2 or T4 disease or those with contralateral mediastinal involvement (N3), a phase III trial is under way to explore concurrent carboplatin as intensification of local therapy and additional systemic treatment. This builds on prior CALGB work demonstrating the benefits of induction chemotherapy prior to radiation for selected patients with stage III disease. For patients with still more advanced disease, a trial evaluating efficacy and cost of two supportive care modalities during intensive chemotherapy is about to begin accrual. Following its completion, the CALGB plans to evaluate new chemotherapy combinations based on one or more of the exciting new agents now being tested for the nonoperative management of non-small cell lung cancer.

Duke Scholars

Published In

Semin Oncol

ISSN

0093-7754

Publication Date

June 1994

Volume

21

Issue

3 Suppl 6

Start / End Page

60 / 65

Location

United States

Related Subject Headings

  • Oncology & Carcinogenesis
  • Lung Neoplasms
  • Humans
  • Clinical Trials as Topic
  • Clinical Protocols
  • Chemotherapy, Adjuvant
  • Carcinoma, Non-Small-Cell Lung
  • Antineoplastic Combined Chemotherapy Protocols
  • 3211 Oncology and carcinogenesis
  • 1112 Oncology and Carcinogenesis
 

Citation

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MLA
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Green, M. R., Kosty, M. P., Muscato, J. J., Graziano, S., Dillman, R. O., Clamon, G. H., & Herndon, J. (1994). Nonoperative management of non-small cell lung cancer: the current cancer and leukemia group B experience. Semin Oncol, 21(3 Suppl 6), 60–65.
Green, M. R., M. P. Kosty, J. J. Muscato, S. Graziano, R. O. Dillman, G. H. Clamon, and J. Herndon. “Nonoperative management of non-small cell lung cancer: the current cancer and leukemia group B experience.Semin Oncol 21, no. 3 Suppl 6 (June 1994): 60–65.
Green MR, Kosty MP, Muscato JJ, Graziano S, Dillman RO, Clamon GH, et al. Nonoperative management of non-small cell lung cancer: the current cancer and leukemia group B experience. Semin Oncol. 1994 Jun;21(3 Suppl 6):60–5.
Green, M. R., et al. “Nonoperative management of non-small cell lung cancer: the current cancer and leukemia group B experience.Semin Oncol, vol. 21, no. 3 Suppl 6, June 1994, pp. 60–65.
Green MR, Kosty MP, Muscato JJ, Graziano S, Dillman RO, Clamon GH, Herndon J. Nonoperative management of non-small cell lung cancer: the current cancer and leukemia group B experience. Semin Oncol. 1994 Jun;21(3 Suppl 6):60–65.
Journal cover image

Published In

Semin Oncol

ISSN

0093-7754

Publication Date

June 1994

Volume

21

Issue

3 Suppl 6

Start / End Page

60 / 65

Location

United States

Related Subject Headings

  • Oncology & Carcinogenesis
  • Lung Neoplasms
  • Humans
  • Clinical Trials as Topic
  • Clinical Protocols
  • Chemotherapy, Adjuvant
  • Carcinoma, Non-Small-Cell Lung
  • Antineoplastic Combined Chemotherapy Protocols
  • 3211 Oncology and carcinogenesis
  • 1112 Oncology and Carcinogenesis