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Applying a conceptual model for examining health-related quality of life in long-term breast cancer survivors: CALGB study 79804.

Publication ,  Journal Article
Paskett, ED; Herndon, JE; Day, JM; Stark, NN; Winer, EP; Grubbs, SS; Pavy, MD; Shapiro, CL; List, MA; Hensley, ML; Naughton, MA; Kornblith, AB ...
Published in: Psychooncology
November 2008

OBJECTIVES: The Survivor's Health and Reaction study used a quality-of-life model adapted for cancer survivors by Dow and colleagues to identify factors related to global health-related quality of life (HRQL) and to document the prevalence of problems and health-oriented behaviors in a follow-up study of breast cancer patients who participated in CALGB 8541. METHODS: A total of 245 survivors (78% of those invited) who were 9.4-16.5 years post-diagnosis completed surveys that inquired about current HRQL, economic, spiritual, physical and psychosocial concerns, and health-oriented behaviors (e.g. smoking, exercise, and supplement use). A regression model was developed to examine factors related to global HRQL across all domains. RESULTS: The regression model revealed that decreased energy levels (odds ratio (OR)=1.05, 95% confidence interval (CI): 1.03, 1.07), having heart disease (OR=5.01, 95% CI: 1.39, 18.1), having two or more co-morbidities (OR=2.39, 95% CI: 1.10, 5.19), and lower social support (OR=1.03, 95% CI: 1.02, 1.05) were associated with lower global HRQL. Factors related to psychological, spiritual, and economic domains were not predictive of global HRQL. Regarding lifestyle changes, some women reported engaging in health-oriented behaviors since their cancer diagnosis, such as improving eating habits (54%), increasing exercise (32%), and reducing/quitting smoking (20%). The most prevalent problems reported by women at follow-up were menopausal symptoms (64%), such as hot flashes and vaginal dryness, osteoporosis (25%), and lymphedema (23%). CONCLUSION: Suggestions are provided to target interventions, such as provider-based strategies, in order to improve HRQL in long-term breast cancer survivors.

Duke Scholars

Published In

Psychooncology

DOI

EISSN

1099-1611

Publication Date

November 2008

Volume

17

Issue

11

Start / End Page

1108 / 1120

Location

England

Related Subject Headings

  • Survivors
  • Spirituality
  • Socioeconomic Factors
  • Social Support
  • Sick Role
  • Randomized Controlled Trials as Topic
  • Quality of Life
  • Oncology & Carcinogenesis
  • Neoplasm Staging
  • Middle Aged
 

Citation

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Paskett, E. D., Herndon, J. E., Day, J. M., Stark, N. N., Winer, E. P., Grubbs, S. S., … Cancer and Leukemia Group B, . (2008). Applying a conceptual model for examining health-related quality of life in long-term breast cancer survivors: CALGB study 79804. Psychooncology, 17(11), 1108–1120. https://doi.org/10.1002/pon.1329
Paskett, Electra D., James E. Herndon, Jeannette M. Day, Nancy N. Stark, Eric P. Winer, Stephen S. Grubbs, Michael D. Pavy, et al. “Applying a conceptual model for examining health-related quality of life in long-term breast cancer survivors: CALGB study 79804.Psychooncology 17, no. 11 (November 2008): 1108–20. https://doi.org/10.1002/pon.1329.
Paskett ED, Herndon JE, Day JM, Stark NN, Winer EP, Grubbs SS, et al. Applying a conceptual model for examining health-related quality of life in long-term breast cancer survivors: CALGB study 79804. Psychooncology. 2008 Nov;17(11):1108–20.
Paskett, Electra D., et al. “Applying a conceptual model for examining health-related quality of life in long-term breast cancer survivors: CALGB study 79804.Psychooncology, vol. 17, no. 11, Nov. 2008, pp. 1108–20. Pubmed, doi:10.1002/pon.1329.
Paskett ED, Herndon JE, Day JM, Stark NN, Winer EP, Grubbs SS, Pavy MD, Shapiro CL, List MA, Hensley ML, Naughton MA, Kornblith AB, Habin KR, Fleming GF, Bittoni MA, Cancer and Leukemia Group B. Applying a conceptual model for examining health-related quality of life in long-term breast cancer survivors: CALGB study 79804. Psychooncology. 2008 Nov;17(11):1108–1120.
Journal cover image

Published In

Psychooncology

DOI

EISSN

1099-1611

Publication Date

November 2008

Volume

17

Issue

11

Start / End Page

1108 / 1120

Location

England

Related Subject Headings

  • Survivors
  • Spirituality
  • Socioeconomic Factors
  • Social Support
  • Sick Role
  • Randomized Controlled Trials as Topic
  • Quality of Life
  • Oncology & Carcinogenesis
  • Neoplasm Staging
  • Middle Aged