Formation of Ordered cellular structures in suspension via label-free negative magnetophoresis

The creation of ordered cellular structures is important for tissue engineering research. Here, we present a novel strategy for the assembly of cells into linear arrangements by negative magnetophoresis using inert, cytocompatible magnetic nanoparticles. In this approach, magnetic nanoparticles dictate the cellular assembly without relying on cell binding or uptake. The linear cell structures are stable and can be further cultured without the magnetic field or nanoparticles, making this an attractive tool for tissue engineering. © 2009 American Chemical Society.

Full Text

Duke Authors

Cited Authors

  • Krebs, MD; Erb, RM; Yellen, BB; Samanta, B; Bajaj, A; Rotello, VM; Alsberg, E

Published Date

  • 2009

Published In

Volume / Issue

  • 9 / 5

Start / End Page

  • 1812 - 1817

PubMed ID

  • 19326920

International Standard Serial Number (ISSN)

  • 1530-6984

Digital Object Identifier (DOI)

  • 10.1021/nl803757u

Citation Source

  • SciVal