Dedifferentiated parosteal osteosarcoma with giant cell tumor component.

Journal Article (Journal Article)

Dedifferentiated parosteal osteosarcoma is characterized histologically by the admixture of low-grade fibroblastic osteosarcoma and a high-grade component typically resembling conventional osteosarcoma or malignant fibrous histiocytoma. We report an unusual distal femoral dedifferentiated parosteal osteosarcoma in which the dedifferentiated component resembled a giant cell tumor of bone. This phenotype is rarely described in the dedifferentiated component of a dedifferentiated parosteal osteosarcoma. The clinical, radiographic, and pathologic features of this unusual tumor are described to further expand the histologic spectrum of dedifferentiated parosteal osteosarcoma.

Full Text

Duke Authors

Cited Authors

  • Cardona, DM; Knapik, JA; Reith, JD

Published Date

  • April 2008

Published In

Volume / Issue

  • 37 / 4

Start / End Page

  • 367 - 371

PubMed ID

  • 18256826

International Standard Serial Number (ISSN)

  • 0364-2348

Digital Object Identifier (DOI)

  • 10.1007/s00256-007-0440-1


  • eng

Conference Location

  • Germany