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Intracarotid propofol testing: a comparative study with amobarbital.

Publication ,  Journal Article
Mikati, MA; Naasan, G; Tarabay, H; El Yamen, S; Baydoun, A; Comair, YG
Published in: Epilepsy Behav
March 2009

Twenty-five consecutive patients who underwent the Wada test using propofol as anesthetic were compared with 15 randomly selected patients who were tested using amobarbital. Time to verbal and nonverbal responses and time to motor power 3/5 did not differ between the two groups (P>0.05). The number of doses received by each patient and the percentage of patients needing more than one dose were significantly greater in the propofol group (P<0.005). Only one patient developed confusion, combativeness, and agitation. Despite the need for multiple doses, our patients had no residual drowsiness within 10 to 15 minutes of the propofol injection. This allowed us to perform the test on both sides on the same day separated only by 45 minutes. Propofol is an effective alternative to amobarbital in the Wada test, and may be used successfully in multiple repeated injections within the same test without significant residual sedation or significant adverse effects.

Duke Scholars

Published In

Epilepsy Behav

DOI

EISSN

1525-5069

Publication Date

March 2009

Volume

14

Issue

3

Start / End Page

503 / 507

Location

United States

Related Subject Headings

  • Young Adult
  • Psychomotor Agitation
  • Propofol
  • Neurology & Neurosurgery
  • Muscle Strength
  • Memory
  • Male
  • Magnetic Resonance Imaging
  • Infusions, Intra-Arterial
  • Humans
 

Citation

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ICMJE
MLA
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Mikati, M. A., Naasan, G., Tarabay, H., El Yamen, S., Baydoun, A., & Comair, Y. G. (2009). Intracarotid propofol testing: a comparative study with amobarbital. Epilepsy Behav, 14(3), 503–507. https://doi.org/10.1016/j.yebeh.2008.12.023
Mikati, Mohamad A., Georges Naasan, Hayssam Tarabay, Sarah El Yamen, Ahmad Baydoun, and Youssef G. Comair. “Intracarotid propofol testing: a comparative study with amobarbital.Epilepsy Behav 14, no. 3 (March 2009): 503–7. https://doi.org/10.1016/j.yebeh.2008.12.023.
Mikati MA, Naasan G, Tarabay H, El Yamen S, Baydoun A, Comair YG. Intracarotid propofol testing: a comparative study with amobarbital. Epilepsy Behav. 2009 Mar;14(3):503–7.
Mikati, Mohamad A., et al. “Intracarotid propofol testing: a comparative study with amobarbital.Epilepsy Behav, vol. 14, no. 3, Mar. 2009, pp. 503–07. Pubmed, doi:10.1016/j.yebeh.2008.12.023.
Mikati MA, Naasan G, Tarabay H, El Yamen S, Baydoun A, Comair YG. Intracarotid propofol testing: a comparative study with amobarbital. Epilepsy Behav. 2009 Mar;14(3):503–507.
Journal cover image

Published In

Epilepsy Behav

DOI

EISSN

1525-5069

Publication Date

March 2009

Volume

14

Issue

3

Start / End Page

503 / 507

Location

United States

Related Subject Headings

  • Young Adult
  • Psychomotor Agitation
  • Propofol
  • Neurology & Neurosurgery
  • Muscle Strength
  • Memory
  • Male
  • Magnetic Resonance Imaging
  • Infusions, Intra-Arterial
  • Humans