Fundamentals of quantitative dynamic contrast-enhanced MR imaging.

Journal Article (Journal Article;Review)

Quantitative analysis of dynamic contrast-enhanced MR imaging (DCE-MR imaging) has the power to provide information regarding physiologic characteristics of the microvasculature and is, therefore, of great potential value to the practice of oncology. In particular, these techniques could have a significant impact on the development of novel anticancer therapies as a promising biomarker of drug activity. Standardization of DCE-MR imaging acquisition and analysis to provide more reproducible measures of tumor vessel physiology is of crucial importance to realize this potential. The purpose of this article is to review the pathophysiologic basis and technical aspects of DCE-MR imaging techniques.

Full Text

Duke Authors

Cited Authors

  • Paldino, MJ; Barboriak, DP

Published Date

  • May 2009

Published In

Volume / Issue

  • 17 / 2

Start / End Page

  • 277 - 289

PubMed ID

  • 19406359

Electronic International Standard Serial Number (EISSN)

  • 1557-9786

Digital Object Identifier (DOI)

  • 10.1016/j.mric.2009.01.007


  • eng

Conference Location

  • United States