Fundamentals of quantitative dynamic contrast-enhanced MR imaging.
Published
Journal Article (Review)
Quantitative analysis of dynamic contrast-enhanced MR imaging (DCE-MR imaging) has the power to provide information regarding physiologic characteristics of the microvasculature and is, therefore, of great potential value to the practice of oncology. In particular, these techniques could have a significant impact on the development of novel anticancer therapies as a promising biomarker of drug activity. Standardization of DCE-MR imaging acquisition and analysis to provide more reproducible measures of tumor vessel physiology is of crucial importance to realize this potential. The purpose of this article is to review the pathophysiologic basis and technical aspects of DCE-MR imaging techniques.
Full Text
Duke Authors
Cited Authors
- Paldino, MJ; Barboriak, DP
Published Date
- May 2009
Published In
Volume / Issue
- 17 / 2
Start / End Page
- 277 - 289
PubMed ID
- 19406359
Pubmed Central ID
- 19406359
Electronic International Standard Serial Number (EISSN)
- 1557-9786
Digital Object Identifier (DOI)
- 10.1016/j.mric.2009.01.007
Language
- eng
Conference Location
- United States