Thymoma detection by mediastinal CT: patient with myasthenia gravis.

Journal Article (Journal Article)

The precise role of computed tomography (CT) in evaluating the mediastinum for thymomas in patients with myasthenia gravis is not defined. The only published CT accuracy assessment reports a false-positive rate of 90%. Mediastinal CT was performed in 23 consecutive unselected patients with myasthenia gravis who underwent thymectomy independent of their neurologic status or diagnostic imaging results. Four patients had discrete thymomas; all were detected by CT. Conventional chest radiography and tomography were positive in three and falsely negative in one. In the remaining 19 patients with a normal or atrophic thymus or microscopic hyperplasia, CT was falsely positive in two; conventional chest radiography and tomography were falsely positive in three. Mediastinal CT is an accurate technique for evaluation of thymoma in patients with myasthenia gravis.

Full Text

Duke Authors

Cited Authors

  • Moore, AV; Korobkin, M; Powers, B; Olanow, W; Ravin, CE; Putman, CE; Breiman, RS; Ram, PC

Published Date

  • February 1, 1982

Published In

Volume / Issue

  • 138 / 2

Start / End Page

  • 217 - 222

PubMed ID

  • 6976722

International Standard Serial Number (ISSN)

  • 0361-803X

Digital Object Identifier (DOI)

  • 10.2214/ajr.138.2.217


  • eng

Conference Location

  • United States