Metastatic melanoma in the thorax: report of 130 patients.

Journal Article (Journal Article)

Early detection of metastatic melanoma has become more important as newer and more effective therapeutic regimens are used. Between 1970 and 1980, 1,600 patients were treated at one institution for malignant melanoma. Of these, 260 (16.3%) developed thoracic metastasis. Satisfactory chest radiographs were available for analysis in 130 of 260 patients. The patterns of the intrathoracic metastasis include multiple pulmonary nodules (52 patients), solitary nodule (26), miliary pattern (two), mediastinal and/or hilar adenopathy (nine), pleural effusion (three), lytic bony lesions (one), extra-pleural mass (one), and combined lesions (36). Both the staging of melanoma and the radiographic pattern of thoracic metastasis seemed to prognosticate the survival rate of these patients. Miliary metastasis and bone destruction implied a grave prognosis. Patients with a solitary lung nodule had the best survival experience. Immunotherapy, chemotherapy, and surgery of selected distal metastases significantly improved the survival of most of these patients.

Full Text

Duke Authors

Cited Authors

  • Chen, JT; Dahmash, NS; Ravin, CE; Heaston, DK; Putman, CE; Seigler, HF; Reed, JC

Published Date

  • August 1981

Published In

Volume / Issue

  • 137 / 2

Start / End Page

  • 293 - 298

PubMed ID

  • 6789636

International Standard Serial Number (ISSN)

  • 0361-803X

Digital Object Identifier (DOI)

  • 10.2214/ajr.137.2.293


  • eng

Conference Location

  • United States