Time from positive screening fecal occult blood test to colonoscopy and risk of neoplasia.

Journal Article (Journal Article)

There is no guideline defining the optimal time from a positive screening fecal occult blood test to follow-up colonoscopy. We reviewed records of 231 consecutive primary care patients who received a colonoscopy within 18 months of a positive fecal occult blood test. We examined the relationship between time to colonoscopy and risk of neoplasia on colonoscopy using a logistic regression analysis adjusting for potential confounders such as age, race, and gender. The mean time to colonoscopy was 236 days. Longer time to colonoscopy (OR = 1.10, P = 0.01) and older age (OR 1.04, P = 0.01) were associated with higher odds of neoplasia. The association of time with advanced neoplasia was positive, but not statistically significant (OR 1.07, P = 0.14). In this study, a longer interval to colonoscopy after fecal occult blood test was associated with an increased risk of neoplasia. Determining the optimal interval for follow-up is desirable and will require larger studies.

Full Text

Duke Authors

Cited Authors

  • Gellad, ZF; Almirall, D; Provenzale, D; Fisher, DA

Published Date

  • November 2009

Published In

Volume / Issue

  • 54 / 11

Start / End Page

  • 2497 - 2502

PubMed ID

  • 19093199

Pubmed Central ID

  • PMC3726721

Electronic International Standard Serial Number (EISSN)

  • 1573-2568

Digital Object Identifier (DOI)

  • 10.1007/s10620-008-0653-8


  • eng

Conference Location

  • United States