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Measurement of the transverse strain tensor in the coronary arterial wall from clinical intravascular ultrasound images.

Publication ,  Journal Article
Liang, Y; Zhu, H; Gehrig, T; Friedman, MH
Published in: Journal of biomechanics
October 2008

Atherosclerotic plaque rupture is the major cause of acute coronary syndromes. Currently, there is no reliable diagnostic tool to predict plaque rupture. Knowledge of plaque mechanical properties based on local artery wall strain measurements would be useful for characterizing its composition and predicting its vulnerability. Due to cardiac motion, strain estimation in clinical intravascular ultrasound (IVUS) images is extremely challenging. A method is presented to estimate cross-sectional coronary artery wall strain in response to cardiac pulsatile pressure using clinically acquired IVUS images, which are acquired in continuous pullback mode. First, cardiac phase information is retrieved retrospectively from an IVUS image sequence using an image-based gating method, and image sub-sequences at systole and diastole are extracted. Then, images at branch sites are used as landmarks to align the two image sub-sequences. Finally, the paired images at each site are registered to measure the 2D strain tensor of the coronary artery cross-section. This method has been successfully applied to IVUS images of a left anterior descending (LAD) coronary artery acquired clinically during a standard procedure. Such complete strain information should be useful for identifying vulnerable plaque.

Duke Scholars

Published In

Journal of biomechanics

DOI

EISSN

1873-2380

ISSN

0021-9290

Publication Date

October 2008

Volume

41

Issue

14

Start / End Page

2906 / 2911

Related Subject Headings

  • Ultrasonography, Interventional
  • Stress, Mechanical
  • Sensitivity and Specificity
  • Models, Cardiovascular
  • Image Interpretation, Computer-Assisted
  • Humans
  • Elasticity Imaging Techniques
  • Elastic Modulus
  • Coronary Vessels
  • Computer Simulation
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Liang, Y., Zhu, H., Gehrig, T., & Friedman, M. H. (2008). Measurement of the transverse strain tensor in the coronary arterial wall from clinical intravascular ultrasound images. Journal of Biomechanics, 41(14), 2906–2911. https://doi.org/10.1016/j.jbiomech.2008.08.004
Liang, Yun, Hui Zhu, Thomas Gehrig, and Morton H. Friedman. “Measurement of the transverse strain tensor in the coronary arterial wall from clinical intravascular ultrasound images.Journal of Biomechanics 41, no. 14 (October 2008): 2906–11. https://doi.org/10.1016/j.jbiomech.2008.08.004.
Liang Y, Zhu H, Gehrig T, Friedman MH. Measurement of the transverse strain tensor in the coronary arterial wall from clinical intravascular ultrasound images. Journal of biomechanics. 2008 Oct;41(14):2906–11.
Liang, Yun, et al. “Measurement of the transverse strain tensor in the coronary arterial wall from clinical intravascular ultrasound images.Journal of Biomechanics, vol. 41, no. 14, Oct. 2008, pp. 2906–11. Epmc, doi:10.1016/j.jbiomech.2008.08.004.
Liang Y, Zhu H, Gehrig T, Friedman MH. Measurement of the transverse strain tensor in the coronary arterial wall from clinical intravascular ultrasound images. Journal of biomechanics. 2008 Oct;41(14):2906–2911.
Journal cover image

Published In

Journal of biomechanics

DOI

EISSN

1873-2380

ISSN

0021-9290

Publication Date

October 2008

Volume

41

Issue

14

Start / End Page

2906 / 2911

Related Subject Headings

  • Ultrasonography, Interventional
  • Stress, Mechanical
  • Sensitivity and Specificity
  • Models, Cardiovascular
  • Image Interpretation, Computer-Assisted
  • Humans
  • Elasticity Imaging Techniques
  • Elastic Modulus
  • Coronary Vessels
  • Computer Simulation