Modulation of conduction velocity by nonmyocytes in the low coupling regime.

Journal Article (Journal Article)

This paper explores the conditions under which nonmyocytes, when electrically coupled to myocytes, act as a passive load during the depolarization phase. Using theoretical arguments and numerical simulations in a tissue incorporating fibroblasts, the passive load approximation is shown to be accurate at low coupling conductances (< 2 nS). In this case, the effect on conduction velocity can be expressed as a function of the elevation in resting potential and the coupling only.

Full Text

Duke Authors

Cited Authors

  • Jacquemet, V; Henriquez, CS

Published Date

  • March 2009

Published In

Volume / Issue

  • 56 / 3

Start / End Page

  • 893 - 896

PubMed ID

  • 19389687

Pubmed Central ID

  • PMC3563360

Electronic International Standard Serial Number (EISSN)

  • 1558-2531

International Standard Serial Number (ISSN)

  • 0018-9294

Digital Object Identifier (DOI)

  • 10.1109/tbme.2008.2006028


  • eng