Modulation of conduction velocity by nonmyocytes in the low coupling regime.

Journal Article (Journal Article)

This paper explores the conditions under which nonmyocytes, when electrically coupled to myocytes, act as a passive load during the depolarization phase. Using theoretical arguments and numerical simulations in a tissue incorporating fibroblasts, the passive load approximation is shown to be accurate at low coupling conductances (< 2 nS). In this case, the effect on conduction velocity can be expressed as a function of the elevation in resting potential and the coupling only.

Full Text

Duke Authors

Henriquez, Craig S.

Cited Authors

Jacquemet, V; Henriquez, CS

Published Date

March 2009

Published In

Ieee Transactions on Bio Medical Engineering

Volume / Issue

56 / 3

Start / End Page

893 - 896

PubMed ID

19389687

Pubmed Central ID

PMC3563360

Electronic International Standard Serial Number (EISSN)

1558-2531

International Standard Serial Number (ISSN)

0018-9294

Digital Object Identifier (DOI)

10.1109/tbme.2008.2006028

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