Detailed visualization of the anterior segment using fourier-domain optical coherence tomography.
Journal Article (Journal Article)
OBJECTIVE: To study details of the anterior chamber drainage angle using Fourier-domain optical coherence tomography in healthy subjects and patients with angle abnormalities. METHODS: A high-speed anterior segment optical coherence tomography prototype was developed using a 1310-nm-wavelength swept light source. Six healthy subjects and 6 patients with glaucoma were imaged in an observational cross-sectional study. RESULTS: Schlemm's canal and the trabecular meshwork were visualized in all of the patients. Fifteen-millimeter scans enabled entire anterior segment visualization providing configuration details of the iris with respect to the angle. Four-millimeter scans permitted detailed views of the angle configuration and its structures. Volumetric imaging was possible and Schlemm's canal was visualized along part of its circumference. CONCLUSION: Anterior segment Fourier-domain optical coherence tomography permits detailed noncontact imaging of the angle and its structures, providing a tool to improve our understanding of the pathogenesis of narrow-angle glaucoma.
Full Text
Duke Authors
Cited Authors
- Asrani, S; Sarunic, M; Santiago, C; Izatt, J
Published Date
- June 2008
Published In
Volume / Issue
- 126 / 6
Start / End Page
- 765 - 771
PubMed ID
- 18541838
Pubmed Central ID
- 18541838
Electronic International Standard Serial Number (EISSN)
- 1538-3601
Digital Object Identifier (DOI)
- 10.1001/archopht.126.6.765
Language
- eng
Conference Location
- United States