Detailed visualization of the anterior segment using fourier-domain optical coherence tomography.

Journal Article (Journal Article)

OBJECTIVE: To study details of the anterior chamber drainage angle using Fourier-domain optical coherence tomography in healthy subjects and patients with angle abnormalities. METHODS: A high-speed anterior segment optical coherence tomography prototype was developed using a 1310-nm-wavelength swept light source. Six healthy subjects and 6 patients with glaucoma were imaged in an observational cross-sectional study. RESULTS: Schlemm's canal and the trabecular meshwork were visualized in all of the patients. Fifteen-millimeter scans enabled entire anterior segment visualization providing configuration details of the iris with respect to the angle. Four-millimeter scans permitted detailed views of the angle configuration and its structures. Volumetric imaging was possible and Schlemm's canal was visualized along part of its circumference. CONCLUSION: Anterior segment Fourier-domain optical coherence tomography permits detailed noncontact imaging of the angle and its structures, providing a tool to improve our understanding of the pathogenesis of narrow-angle glaucoma.

Full Text

Duke Authors

Cited Authors

  • Asrani, S; Sarunic, M; Santiago, C; Izatt, J

Published Date

  • June 2008

Published In

Volume / Issue

  • 126 / 6

Start / End Page

  • 765 - 771

PubMed ID

  • 18541838

Pubmed Central ID

  • PMC2756510

Electronic International Standard Serial Number (EISSN)

  • 1538-3601

Digital Object Identifier (DOI)

  • 10.1001/archopht.126.6.765


  • eng

Conference Location

  • United States