Diffuse reflectance spectroscopy with a self-calibrating fiber optic probe.


Journal Article

Calibration of the diffuse reflectance spectrum for instrument response and time-dependent fluctuation as well as interdevice variations is complicated, time consuming, and potentially inaccurate. We describe a novel fiber optic probe with a real-time self-calibration capability that can be used for tissue optical spectroscopy. The probe was tested in a number of liquid phantoms over a relevant range of tissue optical properties. Absorption and scattering coefficients are extracted with an average absolute error and standard deviation of 6.9%+/-7.2% and 3.5%+/-1.5%, respectively.

Full Text

Cited Authors

  • Yu, B; Fu, H; Bydlon, T; Bender, JE; Ramanujam, N

Published Date

  • August 15, 2008

Published In

Volume / Issue

  • 33 / 16

Start / End Page

  • 1783 - 1785

PubMed ID

  • 18709086

Pubmed Central ID

  • 18709086

International Standard Serial Number (ISSN)

  • 0146-9592

Digital Object Identifier (DOI)

  • 10.1364/ol.33.001783


  • eng

Conference Location

  • United States