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Is an increased dwell time of a peripherally inserted catheter associated with an increased risk of bloodstream infection in infants?

Publication ,  Journal Article
Smith, PB; Benjamin, DK; Cotten, CM; Schultz, E; Guo, R; Nowell, L; Smithwick, ML; Thornburg, CD
Published in: Infect Control Hosp Epidemiol
August 2008

OBJECTIVE: To estimate the risk of bloodstream infection associated with catheter dwell time in infants. DESIGN: Retrospective study. SETTING: Duke University Medical Center neonatal intensive care unit, an academic, level 3 nursery in Durham, North Carolina. METHODS: A case of catheter-associated bloodstream infection was defined as one that occurred in an infant whose culture-positive blood sample was collected more than 24 hours after catheter insertion or within 72 hours after catheter removal. We used multivariable logistic regression to control for the catheter's position and dwell time as well as the infant's sex, gestational age, age at time of catheter insertion, birth weight, and weight at time of catheter insertion. RESULTS: We identified 135 cases of catheter-associated bloodstream infection. The mean catheter dwell time was 12.2 days (range, 0-113 days), and the mean time to bloodstream infection was 10.8 days (range, 1-57 days). An increase in catheter dwell time was associated with a lower risk of bloodstream infection (odds ratio, 0.975 [95% confidence interval, 0.954-0.996]; P = .02). CONCLUSION: No increased risk of catheter-associated bloodstream infection was observed with increased catheter dwell time. This may have been due to the infant's improved nutrition, decreased need for other invasive devices, and maturing skin and immune system as catheter dwell time increased.

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Published In

Infect Control Hosp Epidemiol

DOI

EISSN

1559-6834

Publication Date

August 2008

Volume

29

Issue

8

Start / End Page

749 / 753

Location

United States

Related Subject Headings

  • Time Factors
  • Risk Assessment
  • North Carolina
  • Male
  • Intensive Care Units, Neonatal
  • Infant, Very Low Birth Weight
  • Infant, Premature, Diseases
  • Infant, Premature
  • Infant, Newborn
  • Infant, Extremely Low Birth Weight
 

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Smith, P. B., Benjamin, D. K., Cotten, C. M., Schultz, E., Guo, R., Nowell, L., … Thornburg, C. D. (2008). Is an increased dwell time of a peripherally inserted catheter associated with an increased risk of bloodstream infection in infants? Infect Control Hosp Epidemiol, 29(8), 749–753. https://doi.org/10.1086/589905
Smith, P Brian, Daniel K. Benjamin, C Michael Cotten, Eric Schultz, Rose Guo, Lisa Nowell, Mary Laura Smithwick, and Courtney D. Thornburg. “Is an increased dwell time of a peripherally inserted catheter associated with an increased risk of bloodstream infection in infants?Infect Control Hosp Epidemiol 29, no. 8 (August 2008): 749–53. https://doi.org/10.1086/589905.
Smith PB, Benjamin DK, Cotten CM, Schultz E, Guo R, Nowell L, et al. Is an increased dwell time of a peripherally inserted catheter associated with an increased risk of bloodstream infection in infants? Infect Control Hosp Epidemiol. 2008 Aug;29(8):749–53.
Smith, P. Brian, et al. “Is an increased dwell time of a peripherally inserted catheter associated with an increased risk of bloodstream infection in infants?Infect Control Hosp Epidemiol, vol. 29, no. 8, Aug. 2008, pp. 749–53. Pubmed, doi:10.1086/589905.
Smith PB, Benjamin DK, Cotten CM, Schultz E, Guo R, Nowell L, Smithwick ML, Thornburg CD. Is an increased dwell time of a peripherally inserted catheter associated with an increased risk of bloodstream infection in infants? Infect Control Hosp Epidemiol. 2008 Aug;29(8):749–753.
Journal cover image

Published In

Infect Control Hosp Epidemiol

DOI

EISSN

1559-6834

Publication Date

August 2008

Volume

29

Issue

8

Start / End Page

749 / 753

Location

United States

Related Subject Headings

  • Time Factors
  • Risk Assessment
  • North Carolina
  • Male
  • Intensive Care Units, Neonatal
  • Infant, Very Low Birth Weight
  • Infant, Premature, Diseases
  • Infant, Premature
  • Infant, Newborn
  • Infant, Extremely Low Birth Weight