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Burn wound sepsis: effect of delayed treatment with topical chemotherapy on survival.

Publication ,  Journal Article
Salisbury, RE; Bevin, AG; Steinkraus, GE; Enterline, DS
Published in: J Trauma
February 1980

Using a standardized laboratory rat model of burn wound sepsis, a regimen of once a day application of Silvadene has been found to be more effective treatment than Sulfamylon or cerium-Silvadene. Delaying treatment following infection resulted in decreased survival. Possible reasons for difference in mortality are once-daily application, or perhaps a change in sensitivity between drugs and the infective organism (Ps. aeruginosa) over time.

Duke Scholars

Published In

J Trauma

ISSN

0022-5282

Publication Date

February 1980

Volume

20

Issue

2

Start / End Page

120 / 122

Location

United States

Related Subject Headings

  • Wound Infection
  • Time Factors
  • Sulfadiazine
  • Silver Sulfadiazine
  • Rats
  • Pseudomonas Infections
  • Mafenide
  • Emergency & Critical Care Medicine
  • Disease Models, Animal
  • Cerium
 

Citation

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Chicago
ICMJE
MLA
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Salisbury, R. E., Bevin, A. G., Steinkraus, G. E., & Enterline, D. S. (1980). Burn wound sepsis: effect of delayed treatment with topical chemotherapy on survival. J Trauma, 20(2), 120–122.
Salisbury, R. E., A. G. Bevin, G. E. Steinkraus, and D. S. Enterline. “Burn wound sepsis: effect of delayed treatment with topical chemotherapy on survival.J Trauma 20, no. 2 (February 1980): 120–22.
Salisbury RE, Bevin AG, Steinkraus GE, Enterline DS. Burn wound sepsis: effect of delayed treatment with topical chemotherapy on survival. J Trauma. 1980 Feb;20(2):120–2.
Salisbury, R. E., et al. “Burn wound sepsis: effect of delayed treatment with topical chemotherapy on survival.J Trauma, vol. 20, no. 2, Feb. 1980, pp. 120–22.
Salisbury RE, Bevin AG, Steinkraus GE, Enterline DS. Burn wound sepsis: effect of delayed treatment with topical chemotherapy on survival. J Trauma. 1980 Feb;20(2):120–122.

Published In

J Trauma

ISSN

0022-5282

Publication Date

February 1980

Volume

20

Issue

2

Start / End Page

120 / 122

Location

United States

Related Subject Headings

  • Wound Infection
  • Time Factors
  • Sulfadiazine
  • Silver Sulfadiazine
  • Rats
  • Pseudomonas Infections
  • Mafenide
  • Emergency & Critical Care Medicine
  • Disease Models, Animal
  • Cerium