Burn wound sepsis: effect of delayed treatment with topical chemotherapy on survival.

Journal Article (Journal Article)

Using a standardized laboratory rat model of burn wound sepsis, a regimen of once a day application of Silvadene has been found to be more effective treatment than Sulfamylon or cerium-Silvadene. Delaying treatment following infection resulted in decreased survival. Possible reasons for difference in mortality are once-daily application, or perhaps a change in sensitivity between drugs and the infective organism (Ps. aeruginosa) over time.

Full Text

Duke Authors

Cited Authors

  • Salisbury, RE; Bevin, AG; Steinkraus, GE; Enterline, DS

Published Date

  • February 1, 1980

Published In

Volume / Issue

  • 20 / 2

Start / End Page

  • 120 - 122

PubMed ID

  • 7354493

International Standard Serial Number (ISSN)

  • 0022-5282


  • eng

Conference Location

  • United States