Probiotic administration and the incidence of nosocomial infection in pediatric intensive care: a randomized placebo-controlled trial.


Journal Article

OBJECTIVE: To evaluate the efficacy of probiotics in reducing the rates of nosocomial infection in pediatric intensive care. DESIGN: Randomized, double-blind, placebo-controlled trial. SETTING: A 16-bed pediatric intensive care unit in a university-affiliated children's hospital. PATIENTS: Sixty-one pediatric patients were enrolled from April 2004 until December 2004. Screening of all patients admitted occurred on a daily basis. Patients were excluded if they had the following: evidence/suspicion of intestinal perforation, evidence/suspicion of mechanical gastrointestinal obstruction, absolute neutrophil count

Full Text

Cited Authors

  • Honeycutt, TCB; El Khashab, M; Wardrop, RM; McNeal-Trice, K; Honeycutt, ALB; Christy, CG; Mistry, K; Harris, BD; Meliones, JN; Kocis, KC

Published Date

  • September 2007

Published In

Volume / Issue

  • 8 / 5

Start / End Page

  • 452 - 458

PubMed ID

  • 17693918

Pubmed Central ID

  • 17693918

International Standard Serial Number (ISSN)

  • 1529-7535

Digital Object Identifier (DOI)

  • 10.1097/01.PCC.0000282176.41134.E6


  • eng

Conference Location

  • United States