Pathologic findings following sudden death in an infant with hypertrophic cardiomyopathy and supraventricular tachycardia.

Journal Article (Journal Article)

The cardiac conduction system from infants suddenly dying with hypertrophic cardiomyopathy has not been described. We studied by serial section examination the conduction system from a 13-month old infant also known to have had supraventricular tachycardia. At autopsy, there was cardiomegaly with asymmetric septal hypertrophy. Microscopic examination revealed myofiber disarray around an abnormally formed central fibrous body, numerous nodoventricular fibers to both sides of the ventricular septum, and fibrosis of the left bundle branch. We postulate that supraventricular tachycardia utilized a concealed pathway or the malformed AV junction. Death may have resulted from deranged hemodynamics secondary to supraventricular tachycardia.

Full Text

Duke Authors

Cited Authors

  • Kanter, RJ; Gravatt, A; Bharati, S

Published Date

  • February 1997

Published In

Volume / Issue

  • 8 / 2

Start / End Page

  • 222 - 225

PubMed ID

  • 9048252

International Standard Serial Number (ISSN)

  • 1045-3873

Digital Object Identifier (DOI)

  • 10.1111/j.1540-8167.1997.tb00783.x


  • eng

Conference Location

  • United States