BI-RADS for sonography: positive and negative predictive values of sonographic features.

Journal Article (Journal Article)

OBJECTIVE: The purpose of this study was to assess the positive predictive value (PPV) and negative predictive value (NPV) of features described in the new sonographic BI-RADS lexicon for evaluating solid masses with known histologic diagnoses. MATERIALS AND METHODS: Sonograms of 403 solid lesions were analyzed by one of three dedicated breast radiologists. Each lesion was described using features from the sonographic BI-RADS lexicon. Lesion description and biopsy results were correlated. PPV and NPV were calculated. RESULTS: Histologic results showed that 141 (35%) of 403 masses were malignant. Sonographic BI-RADS descriptors showing high predictive value for malignancy include spiculated margin (86%, 19/22), irregular shape (62%, 102/164), and nonparallel orientation (69%, 75/109). Sonographic BI-RADS descriptors highly predictive of benign lesions include circumscribed margin (90%, 160/178), parallel orientation (78%, 228/294), and oval shape (84%, 200/237). For the sonographic BI-RADS features of mass margin, shape, orientation, lesion boundary, echo pattern, and posterior acoustic features, descriptors chosen were significantly (p < 0.001) different for malignant and benign masses. CONCLUSION: Descriptors from the new sonographic BI-RADS lexicon can be useful in differentiating benign from malignant solid masses.

Full Text

Duke Authors

Cited Authors

  • Hong, AS; Rosen, EL; Soo, MS; Baker, JA

Published Date

  • April 2005

Published In

Volume / Issue

  • 184 / 4

Start / End Page

  • 1260 - 1265

PubMed ID

  • 15788607

International Standard Serial Number (ISSN)

  • 0361-803X

Digital Object Identifier (DOI)

  • 10.2214/ajr.184.4.01841260


  • eng

Conference Location

  • United States