Quantitative Evaluation of Half-Cone-Beam Scan Paths in Triple-Camera Brain SPECT.


Journal Article

In this study related to human brain SPECT imaging, simulation of half-cone-beam (HCB) collimation with different scan paths is performed and compared with simulated fan-beam and parallel-hole circular orbit acquisitions of disk-phantom projection data. Acquisition types are quantitatively evaluated based on the photon detection efficiency, the root-mean-squared error, contrast and signal-to-noise ratio measurements of the reconstructed images. We demonstrate that a triple-camera SPECT system with half-cone-beam collimators and circle-and-helix scan paths can offer up to a 26% efficiency increase over fan-beam, and up to a 128% increase over parallel-hole collimators for equal spatial resolutions, and display no visible axial sampling artifacts in reconstructed disk-phantom images. In addition, we perform qualitative experimental evaluation of triple-HCB circle-and-helix acquisition using a Hoffman 3D brain phantom. Reconstructed brain phantom images show improved quality due to reduced noise and no apparent sampling artifacts. Triple-HCB circle-and-helix SPECT has a potential for improved brain imaging, producing higher image quality with a smaller reconstruction error and better lesion detectability due to increased efficiency for equal spatial resolution compared to conventional fan-beam and parallel-hole SPECT.

Full Text

Duke Authors

Cited Authors

  • Ter-Antonyan, R; Jaszczak, RJ; Bowsher, JE; Greer, KL; Metzler, SD

Published Date

  • October 1, 2008

Published In

Volume / Issue

  • 55 / 5

Start / End Page

  • 2518 - 2526

PubMed ID

  • 19802377

Pubmed Central ID

  • 19802377

International Standard Serial Number (ISSN)

  • 0018-9499

Digital Object Identifier (DOI)

  • 10.1109/TNS.2008.2003255


  • eng

Conference Location

  • United States