Topical minoxidil in early male pattern baldness.

Journal Article (Clinical Trial;Journal Article)

One-hundred twenty-six healthy men with early male pattern baldness completed a 12-month double-blind, controlled trial of 2% and 3% topical minoxidil. Subjects were initially randomly assigned to use placebo or 2% or 3% topical minoxidil. After 4 months of study, the placebo group was crossed over to 3% topical minoxidil. Both objective measurement of hair growth by counting of vellus, terminal, and total hairs in a vertex target balding area and subjective assessment by subject and investigator were done. Treatment of subjects with topical minoxidil for 4 months resulted in a statistically significant increase in terminal hair growth in comparison with placebo therapy. In addition, subjects initially treated with placebo, when crossed over to topical minoxidil, showed a significant increase in the number of terminal hairs. No subject had a net hair loss in the target area during the study. These results indicate that topical minoxidil can increase terminal hair growth in early male pattern baldness.

Full Text

Duke Authors

Cited Authors

  • Olsen, EA; Weiner, MS; Delong, ER; Pinnell, SR

Published Date

  • August 1985

Published In

Volume / Issue

  • 13 / 2 Pt 1

Start / End Page

  • 185 - 192

PubMed ID

  • 3900155

International Standard Serial Number (ISSN)

  • 0190-9622

Digital Object Identifier (DOI)

  • 10.1016/s0190-9622(85)70157-0


  • eng

Conference Location

  • United States